Introduction. Soluble interleukin-2 receptor (sIL-2R) is considered to be an important biomarker that reflects the condition of patients with COVID-19. The establishment its predictive ability in hypertensive COVID-19-associated pneumonia perspective.
 Aim. This study aimed evaluate serum sIL-2R level and establish for severe/critical clinical mortality arterial hypertension.
 Materia...

Background: Liposomes constitute a promising drug delivery vehicle, and are believed to improve drugs’ effectiveness. This study was aimed to compare antihypertensive and vascular modifying activities of liposomal and non-liposomal forms of ascorbic acid. Methods: Forty-nine male Sprague-Dawley rats were randomly divided into seven groups (n=7): A sham vehicle-receiving (Sham-veh), hypert...

objective(s) we investigated the effects of low-dose morphine on nitric oxide (no) and angiogenesis in two-kidney one clip hypertensive (2k1c) rats. materials and methods male rats were divided into two groups: sham-clip operated and 2k1c. each group subdivided into saline and morphine (3 mg/kg i.p. 8 weeks) groups. blood pressure, heart rate, plasma renin activity (pra), no concentration and m...

background: numerous studies have now demonstrated that heart failure with a normal ejection fraction (hfnlef) is common. hypertension is also the most commonly associated cardiac condition in patients with hfnlef. despite the observed link between microalbuminuria, obesity, and cardiovascular disorders, this question has remained ― ‘which is more important for the prediction and prevention of ...

objective(s): auraptene, a monoterpene coumarin from citrus species, exhibits cardioprotective effects.in this study, the effects of auraptene administration were investigated on blood pressure of normotensive and desoxycorticosterone acetate (doca) salt induced hypertensive rats. materials and methods: five weeks administration of auraptene (2, 4, 8 and 16 mg/kg/day) and nifedipine (0.25, 0.5,...

Compared with the normotensive Wistar-Kyoto rat, the spontaneously hypertensive rat exhibits exaggerated alterations in renal sympathetic nerve activity and excretory function during volume expansion (exaggerated natriuresis) and environmental stress (antinatriuresis). The borderline hypertensive rat is the first filial offspring of the spontaneously hypertensive rat and the Wistar-Kyoto rat an...

Background: Lisdexamfetamine is a stimulant used for the treatment of attention-deficit/hyperactivity disorder. Limited data exist regarding the presentation and management of patients with lisdexamfetamine toxicity. Case Presentation: A 17-year-old female with history of prior suicide attempt presented to the emergency department after ingestion of 50 lisdexamfetamine 40 mg capsules which belo...

The reactivity of vascular smooth muscle in helical strips from femoral arteries of normotensive, spontaneously hypertensive, renal hypertensive, and deoxycorticosterone acetate— (DCA-) hypertensive rats was studied. Spontaneous rhythmic contractions occurred in 25 of the 30 strips from the three groups of hypertensive rats and in only 2 of the 10 strips from normotensive rats. Strips from rena...

The purpose of this study was to examine effects of hypertension on mechanics of cerebral arterioles in nongenetic and genetic models of chronic hypertension. Pressure (servo null) and diameter were measured in pial arterioles of anesthetized renal hypertensive rats (one-kidney, one clip), uninephrectomized normotensive rats, spontaneously hypertensive rats, and normotensive Wistar-Kyoto rats. ...