About thirty years ago, the interlukin-6 (IL-6) which is the proinflammatory cytokine, was detected as the differentiation factor of B cell. IL-6 is able to induce maturation in B cells and as a result, B cells achieve the ability to produce antibodies. In addition to immune responses, the role of IL-6 has been known in neurogenesis (neurons and glial cells). The studies have showed that the ab...

Background: Interleukin 6 (IL-6) functions as both a pro-inflammatory cytokine and an anti-inflammatory cytokine. Objective: To evaluate the levels of IL-6 in patients with multiple organ dysfunction syndrome (MODS). Methods: Level of IL-6 was assessed and recorded for 14 days subsequent to the injury in 161 multiple trauma patients. MODS were diagnosed using Marshal Score. Injury Severity Scor...

Objective(s):Although recent investigations have shown chronic inflammation and inflammation-associated diseases might be ameliorated by exercise; little is known about the relation between exercise training with anti/pro-inflammatory cytokines. Materials and Methods: This cross sectional study was conducted to compare interleukin-4 (IL-4), IL-6, IL-10, IL-12, IL-13, interferon gamma (IFN-γ) le...