background: psoriasis is a common chronic and relapsing skin disease with unknown etiology being observed at any age and any gender, having a 1. 5-3% prevalence rate among the general population. psoriatic lesions consist of pruritic and scaling papules, residing on an erythematous base, which are more commonly found on the scalp, extensor surfaces, palms and soles, and the nails. the conventio...

Background and aim: Psoriasis is a chronic inflammatory dermatosis that affects 0.6% to 4.8% of the population. Phototherapy is commonly used in the treatment of this disease. According to the results of previous studies that showed difference in minimal erythema dose between different body sites, it seems that the responses of psoriatic lesions are also different in various body sites. O...

abstract background: psoriasis is a chronic proliferative condition of the skin. its accurate pathogenesis has not been known yet, but interactions between genes and environmental factors have been implicated in its initiation. the role of malassezia in psoriasis is still undetermined, but several reports have associated these lipophilic yeasts with the development of skin lesions in psoriasis....

Psoriasis is an autoimmune disease with skin presentations in different parts of the body. We have noted improvement in psoriasis skin manifestation in a patient with long standing psoriatic lesions of the scalp. We actively sought additional patients with scalp psoriasis and transplanted hair into their scalp into, or in close proximity, of psoriatic lesions in order to elicit a response. Meth...

OBJECTIVES To investigate prospectively how psoriasis fluctuates in pregnancy and post partum and to correlate hormone levels in pregnancy (progesterone and estrogens) with psoriatic change. DESIGN Psoriatic body surface area (BSA) in pregnant patients with psoriasis (study group) and nonpregnant, menstruating patients with psoriasis (control group) were assessed 5 times over a year. Hormone ...

Introduction: Since there is no study in our country about determination the effects of psychogenic factors on psoriasis and because it seems necessary to evaluate the triggering factors of disease in order to lengthen the remission period and decrease the costs and complications, this study was performed to identify the relationship of stress with psoriasis expression and the severity of skin ...

Increasing evidences indicate that the abnormal DNA methylation is involved in the pathogenesis of psoriasis. A number of SNPs in HLA-DRB1 have been found being associated with the risk of psoriasis, however it is unclear that metylation status within HLA-DRB1 in psoriasis. Here, DNA and RNA were obtained from epidermis of 56 patients with plaque psoriasis and 28 healthy volunteers served as th...

Eight patients with psoriatic arthritis entered an open study to determine the efficacy of oral cyclosporin A for their treatment. The starting dose was 3.5 mg/kg daily. Findings after the first six months are reported. One patient withdrew from the study after five months because of tremors, general malaise, and lack of improvement. Seven patients continued through the study, and marked improv...