glipizide has been found to form inclusion complexes with β-cyclodextrin (β-cd) in solution and in solid state. the present study was undertaken to determine a suitable method for scaling up glipizide-β-cd inclusion complex formation and to evaluate the effect of some parameters on the efficiency of complexation. the solid inclusion complexes of glipizide and β-cd were prepared at a molar ratio...

background: the over-expression of recombinant proteins in large amount is important for production of therapeutic proteins and structural study. there are several systems for expression of recombinant proteins. one of the most relevant expression systems is escherichia coli (e. coli). although this organism has many advantages, most of recombinant proteins expressed in e. coli hosts form inclu...

a brief account of the representative and workable industrial minerals namely magnesite, talc and barite in lesser himalaya, is presented here emphasizing their genesis. deposits of magnesite and talc are found associated with neoproterozoic, plateform type, shelf-slope limestone-dolomite host rocks from inner lesser himalayan sequences. field, textural, geochemical signatures and fluid inclusi...

samples of formalin fixed gastrointestinal organs of three month ostrich chicks were submitted to the department of pathology, razi vaccine and serum research institute. histologically hepatitis and pancreatitis with large eosinophilic intra nuclear inclusion bodies were prominent in hepatic and pancreatic cells. these inclusions were suspected as adenovirus inclusion body hepatitis (ibh) in va...

background: the refolding of proteins from inclusion bodies is affected by several factors, including solubilization of inclusion bodies by denaturants, removal of the denaturant, and assistance of refolding by small molecule additives. objectives: the purpose of this study was optimization of recombinant human interferon-b purification in order to achieve higher efficiency, yield, and a produc...

objectives: this paper reviews the current literature on acquired brain injury (abi) with a focus on abi burden, importance of community integration, and community integration definitions suggested by the literature. methods: literature review results: acquired brain injury (abi) is referred to a diverse range of disabilities resulted of injury in different parts of the brain. people with abi a...

this study presents the influence of hydroxypropyl-β-cyclodextrin (hpbcd) on the aqueous solubility of acyl esters of cyproterone. first, a number of esters of cyproterone were synthesized. then the phase solubility analysis of the compounds in the presence of hpbcd was investigated in phosphate buffer solution at a ph of 7.4. to gain a better understanding of the complexation mechanism, the sy...