background: misoprostol, a prostaglandin e1 analogue compared to prostaglandin e2, has the advantage of being inexpensive and stable at room temperature, with its proven efficacy and safety. however studies on the effect of ph on the efficacy of misoprostol have yielded conflicting results. thus its use in the induction of labour in patients with premature rupture of membrane requires further i...

objective: to compare efficacy, safety and tolerance of combination of mifepristone and misoprostol versus misoprostol-only in induction of late intrauterine fetal death (iufd). materials and methods: this prospective study included a consecutive series of 52 women gravid up to fourth with iufd after 28 weeks of gestation between january 2008 and june 2011. women were divided into two groups. f...

' The first account of any artificial method of bringing on premature labour was given to me by Dr. C. Kelly. He informed me that'about the year I756 there was a consultation of the most eminent men in London at that time, to consider of the moral rectitude of, and advantages which may be expected from, this practice, which met with their general approbation. The first case in which it was deem...

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