cellular and molecular pathways link thrombosis and innate immune system during sepsis. extrinsic pathway activation of protease thrombin through fviia and tissue factor (tf) in sepsis help activate its endothelial cell (ec) membrane protease activated receptor 1 (par-1). thrombin adjusts the ec cycle through activation of g proteins (g12/13), and later through rho gefs (guanine nucleotide exch...

introduction: studies have shown that insufficient recovery between sessions causes immune suppression. the aim of this study was to investigate the effect of repeated bouts resistance and endurance exercise on blood leukocytes, lymphocytes, neutrophils, monocytes count and plasma cortisol levels in athlete girls. materials and methods: 9 athlete girls (ages, 20-25 years), participated in the s...

To keep the diversity of antibodies in artificial immune system evolution process, this paper puts forward a kind of increase simulation surname inheritance algorithm based on the clonal selection algorithm, and identification and forecast the Vibration Data about CA6140 horizontal lathe machining slender shaft workpiece prone. The results show that the algorithm has the characteristics of flex...

conclusions the results of our study show that serum zinc level in bronchiectasis patients was lower than the control group and the difference was statistically significant. it seems that the use of zinc supplement can reduce progression of the infectious disease regarding its role in improving the immune system reactions and some unknown mechanisms. therefore, prophylactic and therapeutic use ...

background: occupational exposure to cotton dust, fibers, metal fumes and different chemicals used in the apparel manufacturing industries cause a wide range of physical and psychological health problems in the garment workers that may also affect their immune function. objective: to assess the immune system function in garment workers. methods: a total of 45 workers of a garment factory, and 4...

background : pain is one of the main protests of inflammatory diseases, hence, understanding the mechanisms which involved in the induction and persistence of pain is essential. microglia is a contributing factor in the onset and maintenance of inflammation. increased microglial   activation increases the level of central pro-inflammatory cytokines and the development of central sensitization f...

ae is a serious medical condition in which the immune system attacks the brain, impairing function. with rapid diagnosis and appropriate treatment, many patients recover most or all functions. however, not all patients experience full recovery; with approximately 6% mortality and other patients who never regain significant brain and/or bodily functions. autoimmune encephalitis can produce a wid...

Background: This study evaluated the effects of the maternal immune system stimulation or suppression during the pregnancy on the development of the neonate’s immune system.Methods: A total of 20 female rats were divided into four groups. The groups were treated using Leishmania major, Salmonella typhimurium, Tacrolimus, and sterilized normal saline. The animals were mated after 3-time tr...

the aim of this study was to evaluate the immune system and lymphocyte function in 41 iranian β-thalassemic patients and 50 controls, ages ranging from 2 to 18 years. the patients consisted of 20 splenectomized and 21 non-splenectomized patients. they were treated with desferal, and had received repeated blood transfusion. laboratory investigations included measurement of total t lymphocytes, a...