various adjuvants in combination with different antigens have been utilized as a vaccine candidate against leishmaniasis. however, the search for ideal adjuvants is still pursued due to the inefficiencies of current compounds. in the present study, the effect of imiquimod, as an adjuvant, is studied with soluble leishmania antigens (sla) in balb/c mice. four groups of mice were immunized with s...

  Objective(s): Soluble Leishmania antigens (SLA) provide suitable protection against leishmaniasis in murine model when delivered by an appropriate delivery system. Liposomes have been shown to be suitable vaccine delivery systems against leishmaniasis, however, the phospholipase-A (PLA) activity of SLA is a drawback to prepare a stable liposomal SLA. One strategy to overcome this problem migh...

Service Level Agreement (SLA) is a formal negotiated agreement between a service provider and a customer. The service level management (SLM) is the integrated management of all functionalities in the SLA life cycle. When a customer orders a service from a service provider, an SLA is negotiated and then a contract is made. In the SLA contract, QoS parameters that specify the quality level of ser...

this case study reports a rare variation of the superior laryngeal artery (sla), which is the principal arterial supply of the larynx. the knowledge of the arterial variations is essential for the surgeons to prevent blood loss and postoperative complications. during routine dissection of an adult male cadaver, a rare arterial variation in the sla was seen. in this case, the sla passed through ...

In utility computing, customer requests varying services from software to infrastructure as and when needed. As a result, there are many mobile cloud providers provide this services on demand basis as per current market needs. To ensure compliance and security, these providers establish a contract popularly known as Service Level Agreement (SLA) which states the services and management aspects....

Due to the large variety in computing resources and, consequently, the large number of different types of Service Level Agreements (SLAs), any market for computing resources faces the potential problem of a low market liquidity. To counteract this problem, offering a set of standardized computing resources is appropriate. Each of these standardized computing resources is defined through an SLA ...

In the present work, a hierarchical hybrid micro/nanostructured titanium surface was obtained by sandblasting with large grit and acid etching (SLA), and nanotubes of different diameters (30 nm, 50 nm, and 80 nm) were superimposed by anodization. The effect of each SLA-treated surface decorated with nanotubes (SLA + 30 nm, SLA + 50 nm, and SLA + 80 nm) on osteogenesis was studied in vitro and i...

OBJECTIVE To evaluate the functional results from arthroscopic repair of SLAP lesions through the portal described by O'Brien. METHODS A retrospective evaluation was conducted on 19 shoulders in 18 patients who underwent arthroscopic repair of SLAP lesions through the O'Brien portal between November 2007 and January 2012. RESULTS Nineteen shoulders in 18 patients were evaluated: 16 male pat...

objective(s): leishmaniasis is a complex parasitic disease that represents a major public health problem. despite numerous attempts over the past decades, yet there is no effective vaccine against human leishmaniasis probably due to the lack of suitable adjuvants. in this study, a first generation liposomal-based leishmania vaccine was developed using soluble leishmania major antigens (sla) and...

MHC class I molecules and beta(2)-microglobulin (beta(2)m) are membrane glycoproteins that present peptide Ags to TCRs, and bind to inhibitory and activating receptors on NK cells and other leukocytes. They are involved in the discrimination of self from non-self. Modification of these molecules in the placenta benefits pregnancy, but little is known about their genes in the uterus. We examined...