Vitamin D deficiency is considered as one of the most prevalent healthcare problems in the world. Vitamin D contributes to insulin synthesis and secretion. Deficiency of vitamin D leads to insulin resistance which is the major cause of type 2 diabetes mellitus. We aim to evaluate the effect of treating vitamin D deficiency or insufficiency on serum adiponectin, leptin, and leptin to adiponectin...

purpose the inflammatory state of adipose tissue in obese subjects may be the most important factor linking increased adipose tissue mass to insulin resistance. chemerin is a newly discovered adipokine that plays an important role in macrophage infiltration into adipose tissue and may contribute to the development of inflammation and insulin resistance. we examined the effects of 12 weeks of ae...

Insulin resistance syndrome, also referred to as the metabolic syndrome or syndrome X, refers to a constellation of common metabolic and cardiovascular disorders (e.g. obesity, type 2 diabetes mellitus, hypertension, and dyslipidemia), which are all cardiovascular risk factors. Insulin resistance can be induced by fructose-rich diet in rats. We investigated the effect of vanadyl sulfate (0.2 mg...

Background: The impact of continuous and intermittent training on diabetes mellitus condition and its mechanism is not well understood. The aim of the present study was to assess the changes in glucose uptake after 6 weeks of continuous and intermittent exercise training protocols in healthy and streptozotocin (STZ)-induced diabetic rats. Method: Sixty male al...

Abstract Objective: Insulin resistance and hyperinsulinemia are common among the women with polycystic ovarian syndrome (PCOS). Familial aggregation of PCOS has implications on the role of heredity in this disease. The aim of this study was to evaluate insulin resistance among the fathers, mothers, and siblings of the women with PCOS referring to the clinics affiliated to Shiraz University of ...

Background. Moyenctin, is a new identified myokine and belongs to the CTRPs family which plays role in lipid and glucose metabolism. There is limited information available regarding the effects of exercise training on serum myonectin levels. Objectives. he aim of this study was to investigate the effects of sucrose solution intake and resistance training (RT) with two different volumes on seru...

Objective: The recent study aimed to investigate the effects of chronic aerobic activity on the plasma levels of orexin A, leptin, glucose, insulin, and insulin resistance in males with type 2 diabetes. Materials and Methods: Twenty subjects randomly assigned into control and experimental groups, involving 10 people in each group. Exercise protocol consisted of eight session aerobic exercise...