background resistance exercise is recommended as a useful therapeutic tool for the treatment of type 2 diabetes (t2d); however, the frequency of studies is inadequate to establish the precise mechanisms of any association between them. objectives in this study, we aimed to assess the effect of three months of resistance training on tcf7l2 expression in pancreatic tissues, serum insulin and gluc...

background: in 2-4% of couples in fertile ages, recurrent pregnancy loss (rpl) occurs which consisted one out of 300 pregnancies. the aim of this study was to comparison insulin resistance (ir) in patients with rpl to normal individuals. materials and methods: in a case-controlled, prospective study, 49 non-pregnant, non-diabetic women with early rpl as the case group and 49 non-pregnant, non-d...

to evaluate the effect of intravenous infusion of a soybean based lipid emulsion (lipovenoes 10%) on some blood constituents in sheep, a replicated 2 × 2 latin square design experiment was conducted in four clinically healthy ewes. lipid emulsion (le group) or normal saline (ns group) was infused intravenously at a rate of 0.025 ml kg-1 per min for 6 hr and the concentrations of blood triglycer...

pioglitazone belongs to the thiazolidinedione (tzd) class of antidiabetic agents, with proven efficacy in increasing insulin sensitivity and in the treatment of type 2 diabetes mellitus in humans. pioglitazone has been proposed as a potential feed additive to reduce insulin resistance and consequently some of the metabolic disorders in transition cows. this study was aimed at determining the...

background: obesity has emerged as one of the most serious public health concerns in the 21st century. the consequences of this chronic disorder are serious. bariatric surgery has been shown to eliminate comorbid conditions associated with obesity. currently it is considered to be the only successful, long-term therapy for morbidly obese subjects.rnobjectives: the aim of this study was to evalu...

background: use of glucosamine as an alternative treatment for osteoarthritis is becoming more frequent, including in those who have diabetes at the same time. the results from in vitro and animal studies propose that glucosamine may inversely affect glucose metabolism. however, the recommended dose of oral glucosamine in healthy people or diabetics did not have such effects consistently. the a...

background non-alcoholic fatty liver disease (nafld) is considered as the hepatic manifestation of insulin resistance (ir) syndrome. the effect of insulin sensitizers on liver function tests and metabolic indices in nafld patients is a matter of debate. objectives the aim of study was to compare the effects of two different insulin sensitizers, pioglitazone, and metformin, on liver function tes...

objective(s):the aim of the study was to investigate the relationship between insulin resistance (ir) and leptin (lep) gene polymorphisms in peritoneal dialysis (pd) patients. materials and methods: from july 1, 2011 to august 1, 2011, patients who received chronic pd were chosen and divided into three groups (dm, high homr-ir, and low homr-ir). two pcr products of lep were sequenced and aligne...