results the tlr3 protein in the ach group tended toward reduction although the p value of the comparison between the ach group and hd group was not statistically significant. the tlr3 levels in the hcc, ac, and cir groups were higher than those in the hd and ach groups. tlr3 was not interrelated with all costimulation proteins in the dcs and t cells in all five groups. no group presented any in...

Respiratory syncytial virus (RSV) is the most common cause of infant hospitalizations and severe RSV infections are a significant risk factor for childhood asthma. The pathogenic mechanisms responsible for RSV induced immunopathophysiology remain elusive. Using an age-appropriate mouse model of RSV, we show that IL-33 plays a critical role in the immunopathogenesis of severe RSV, which is assoc...

Brucella melitensis is one of the major zoonotic pathogens worldwide with enormous economic losses as well as considerable human morbidity in endemic areas. The global burden of its incidence in both human and animal populations remains significantly at an alarming rate. The impact of the disease is even multidimensional in nature and not always well understood and significantly complicating ef...

discussion the cholecystojejunocolic anastomosis with intussuscepted valve surgery could be considered as a forthcoming approach in the treatment of intrahepatic cholestasis. case presentation an 11-year-old girl with the diagnosis of pfic underwent cholecystoappendicostomy with myotomy operation. because of anastomosis stricture, she was reoperated with cholecystojejunocolic anastomosis and in...

a 43-year-old man with liver cirrhosis received transjugular intrahepatic portosystemic shunt (tips) for the treatment of recurrent variceal bleeding and f3 esophageal varices. during routine follow up liver ultrasound examination, six months after the implantation, tips occlusion was suspected and tips revision was performed. during the revision, moderate to severe stenosis at the hepatic veno...

The ideal timing and modality of femur shaft fracture fixation in head-injured patients remains a topic of debate. Several groups advocate the immediate definitive fixation of femur fractures ("early total care"), whereas others support the concept of "damage control orthopaedics" with temporary fracture fixation by means of external fixation and staged, planned conversion to internal fixation....