introduction: shorter hospital stay and less pain in comparison to open surgery considered to be major benefits for laparoscopic cholecystectomy. we compared the effect of intraperitoneal hydrocortisone plus bupivacaine with bupivacaine alone on pain relief following laparoscopic cholecystectomy.  methods: sixty two patients participated in this double-blind, randomized clinical trial. patients...

conclusions we conclude that intraperitoneal hydrocortisone instillation caused leukocytosis and is thus suggested not to be used in immune-compromised patients. results the study was completed by 120 patients. patients who received intraperitoneal hydrocortisone and hydrocortisone plus bupivacaine had higher white blood cell (wbc) count (p < 0.0001). the patients were similar with respect to d...

results sixty patients completed the study. patients in the hydrocortisone group had no statistically significant abdominal and shoulder pain scores compared to the bupivacaine group. the patients were similar regarding postoperative analgesic requirements, return of bowel function, nausea and vomiting. no adverse effect was detected in either group. background postoperative pain is a major com...

 Introduction: shorter hospital stay and less pain in comparison to open surgery considered to be major benefits for laparoscopic cholecystectomy. We compared the effect of intraperitoneal hydrocortisone plus bupivacaine with bupivacaine alone on pain relief following laparoscopic cholecystectomy.  Methods: Sixty two patients participated in this double-blind, randomized clinical trial. Pati...

BACKGROUND Postoperative pain is a major complaint following laparoscopic cholecystectomy. OBJECTIVES The aim of this study was to compare the impact of intraperitoneal hydrocortisone with intraperitoneal bupivacaine on pain relief after laparoscopic cholecystectomy. PATIENTS AND METHODS In a double blind clinical trial, 63 candidates for laparoscopic cholecystectomy were randomly allocated...

BACKGROUND Laparoscopic cholecystectomy is associated with shorter hospital stay and less pain in comparison to open surgery. The aim of this study was to evaluate the effect of intraperitoneal hydrocortisone on pain relief following laparoscopic cholecystectomy. METHODS Sixty two patients were enrolled in a double-blind, randomized clinical trial. Patients randomly received intraperitoneal i...

Within 3 hr after the intraperitoneal administration of hydrocortisone to female rats, a new leucine-accepting tRNA and a new leucyl-tRNA synthetase activity appear in the liver cytosol. The new isoaccepting tRNA can be acylated only with the synthetase derived from livers of hormone-treated animals. Both components are transient; by 12 hr after hydrocortisone administration, the isoaccepting t...

The intraperitoneal injection of pristane (2,6,10,14-tetramethylpentadecane) produces an environment conductive to primary plasmacytoma growth in as few as 3 days. After pristane injection, the total free peritoneal cell population increases from a normal value of 1.55 X 10(6) to 5.28 X 10(6) and remains at this elevated level for at least 50 days. The adherent peritoneal cell population, compo...