Administering diazepam intravenously or rectally in an adult with status epilepticus can be difficult and time consuming. The aim of this study was to examine whether intranasal diazepam is an effective alternative to intravenous diazepam when treating status epilepticus. We undertook a retrospective cohort study based on the medical records of 19 stroke patients presenting with status epilepti...

In order to compare rectal and intravenous(IV) administration of diazepam for management of convulsions,a prospective cross-sectional case-control study was conducted on 94 convulsive infants and children referring to the Emergency department of the university hospital No.1 in Kerman.all children were randomly divided into two groups.the patients were matched with regard to the cause,type,durat...

OBJECTIVE To compare the safety and efficacy of midazolam given intranasally with diazepam given intravenously in the treatment of children with prolonged febrile seizures. DESIGN Prospective randomised study. SETTING Paediatric emergency department in a general hospital. SUBJECTS 47 children aged six months to five years with prolonged febrile seizure (at least 10 minutes) during a 12 mo...

OBJECTIVE Serial seizures occur commonly in inpatient epileptic children. This type of seizure due to its characteristics has a significant impact on the patient's health. Untreated serial seizures lead to status epilepticus; therefore, finding a more effective treatment for such patients is essential. This study was performed to compare the outcome of intermittent intravenous diazepam in the p...

The effect on interictal electroencephalographic epileptic activity of intravenous flumazenil (Ro 15-1788), a benzodiazepine antagonist and potential antiepileptic drug, was studied in 10 patients. Comparison was made with intravenous diazepam (10 mg) and placebo using a single-blind, single-dose, cross-over design. A dose of 3 mg flumazenil was well tolerated and produced a significantly great...

OBJECTIVE to compare clinical and cost effectiveness of midazolam and diazepam for urgent intubation. METHODS patients admitted to the Central ICU of the Santa Casa Hospital Complex in Porto Alegre, over the age of 18 years, undergoing urgent intubation during 6 months were eligible. Patients were randomized in a single-blinded manner to either intravenous diazepam or midazolam. Diazepam was ...