A gram-scale synthesis of terminally-branched iso-fatty acids (iso-C12-C19) was developed commencing with methyl undec-10-enoate (methyl undecylenate) (for iso-C12-C14) or the C15 and C16 lactones pentadecanolide (for iso-C15-C17) and hexadecanolide (for iso-C18-C19). Central to the approaches outlined is the two-step construction of the terminal isopropyl group through addition of methylmagnes...

Developing high-quality asynchronous store-and-forward telemedicine systems (ASFTSs) remains a challenge. However, there is no accepted understanding as to what are the important quality characteristics for this type of software system and/or what defines a mature software process for producing high-quality ASTFSs. Through adopting a multi-step research methodology, we define a quality model fo...

BACKGROUND Pretreatment with the angiotensin-converting inhibitor captopril or volatile anesthetic isoflurane has, respectively, been shown to attenuate myocardial ischemia reperfusion (MI/R) injury in rodents and in patients. It is unknown whether or not captopril pretreatment and isoflurane preconditioning (Iso) may additively or synergistically attenuate MI/R injury. METHODS AND RESULTS Pa...

The current system of International Standards (ISO) is assessed to consider whether standards are fit for purpose for the future in the context of climate change. ISO 7243, ISO 7933 and ISO 9886 provide the current ISO system for the assessment of heat stress. These involve a simple monitoring index, an analytical approach and physiological monitoring, respectively. The system relies on accurat...

The paper addresses the issue of an efficient implementation and utilization of new management system parts into an existing landscape of standardized management system on the example of the integration of an energy management system (ISO 50001) into a quality management system (ISO 9001) and an environmental management system (ISO 14001). Therefore we conduct a comparative analysis of the ISO ...

Objective(s): Existing studies have demonstrated that intravenous and intramyocardial-administrated mesenchymal stem cells (MSCs) lead to tissue repair after cardiac disorders. We compared the efficiency of both administration methods.Materials and Methods: A rat model of isoproterenol-induced heart failure (ISO-HF) was established to co...

ISO/IEC 9126 (1991) established a practical way of decomposing software quality into a set of characteristics and subcharacteristics. Reconciling this approach to quality with a new standard for usability (ISO 9241-11) has led to a comprehensive framework for software product quality which is being incorporated in a revision to ISO/IEC 9126. The new framework defines three perspectives: interna...

There are several different standard conventions for specifying a locale, and the first decision is which convention to use. PhET specifies a locale using codes defined by the International Standards Organization (ISO). ISO 639-1 defines language codes [3], while ISO 3166-1 defines country codes [4]. While there are other standards, these are the most commonly-used definitions. An example of a ...

Özet. İNNOVA Bilişim Çözümleri A.Ş. bir Türk Telekom Grup şirketi olup; TSE-ISO-EN ISO 9001, ISO/IEC 20000, ISO/IEC 27001 ve TS ISO/IEC 15504 SPICE Seviye 2 uluslararası sertifikasyonlarına sahiptir. Bu model ve standartlara uygun olarak uygulama geliştirme süreçleri yürütülmektedir. Uygulama geliştirme süreçlerinden yazılım güvenilirliği; yazılımın başarısını gösteren en önemli kalite faktörle...

Web Portals are increasingly being used for important tasks, at a work, personal or leisure related issues. Since Web Portals provide with applications, services and information, their levels of quality are an important prerequisite for their success, and hence, a way to ensure that they do not disappear as a consequence of their not having been used. According to the ISO, there are various per...