نتایج جستجو برای: itch

تعداد نتایج: 2561  

Journal: :Journal of neurophysiology 2007
Siri G Leknes Susanna Bantick Carolyn M Willis John D Wilkinson Richard G Wise Irene Tracey

Intense itch and urge to scratch are the major symptoms of many chronic skin ailments, which are increasingly common. Vicious itch-scratch cycles are readily established and may diminish quality of life for those afflicted. We investigated peripheral and central processing of two types of itch sensation elicited by skin-prick tests of histamine and allergen solutions. Itch-related skin blood fl...

2006
Siri G. Leknes Susanna Bantick Carolyn M. Willis John D. Wilkinson Richard G. Wise Irene Tracey

1 Intense itch and urge to scratch are the major symptoms of many chronic skin ailments, which are increasingly common. Vicious itch-scratch cycles are readily established and may diminish quality of life for those afflicted. We investigated peripheral and central processing of two types of itch sensation, elicited by skin prick tests of histamine and allergen solutions. Itch-related skin blood...

Journal: :iranian red crescent medical journal 0
gong shuhui department of neurosurgery, sichuan university, west china hospital, p. r. china liu jiagang department of neurosurgery, sichuan university, west china hospital, p. r. china huang siqing department of neurosurgery, sichuan university, west china hospital, p. r. china; department of neurosurgery, sichuan university, west china hospital, p. r. china. tel: +86-15708465262, fax: +28-85422488 chen haifeng department of neurosurgery, sichuan university, west china hospital, p. r. china tang qingrong the third people’s hospital of shenzhen, shenzhen, p. r. china zhao bohao department of neurosurgery, sichuan university, west china hospital, p. r. china

conclusions ica with trigeminal neuralgia and local neuropathic itch is very rarely encountered in clinical practice. as it is not always diagnosed at first, some patients miss the best treatment period. therefore, we call for emphasis to be placed on early diagnosis and timely surgical treatment. introduction intramedullary cavernous angioma (ica) is a rare lesion of the spinal cord, represent...

Journal: :Pain 2011
Antoinette I M van Laarhoven Michiel L Vogelaar Oliver H Wilder-Smith Piet L C M van Riel Peter C M van de Kerkhof Floris W Kraaimaat Andrea W M Evers

Physical complaints, such as pain, can be effectively reduced by placebo effects through induction of positive expectations, or increased by nocebo effects through induction of negative expectations. In the present study, verbally induced nocebo and placebo effects on itch were experimentally investigated for the first time. In part 1, the role of verbal suggestions in inducing nocebo effects o...

Journal: :Cerebral cortex 2014
Vitaly Napadow Ang Li Marco L Loggia Jieun Kim Peter C Schalock Ethan Lerner Thanh-Nga Tran Johannes Ring Bruce R Rosen Ted J Kaptchuk Florian Pfab

Itch is an aversive sensory experience and while systemic therapies, such as acupuncture, have shown promise in alleviating itch in patients suffering from chronic itch, their antipruritic mechanisms are unknown. As several lines of evidence implicate brain-focused mechanisms, we applied functional magnetic resonance imaging and our validated temperature-modulation itch model to evaluate the un...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2007
Lisa M Johanek Richard A Meyer Tim Hartke Joseph Greg Hobelmann David N Maine Robert H LaMotte Matthias Ringkamp

The neuronal pathways for itch have been characterized mainly based on responses to histamine. Intracutaneous application of histamine produces intense itch and a large area of axon-reflexive vasodilation ("flare") around the application site. Both phenomena are thought to be mediated through neuronal activity in itch-specific, mechanoinsensitive C-fiber afferents (CMi). However, mechanical and...

2013
Astrid Stumpf Markus Burgmer Gudrun Schneider Gereon Heuft Martin Schmelz Ngoc Quan Phan Sonja Ständer Bettina Pfleiderer

BACKGROUND Even though itch is a common syndrome of many diseases there is only little knowledge about sex and gender differences in pruritus, especially in central itch perception and modulation. To our knowledge, this is the first fMRI study examining sex differences in perception and its modulation by distraction. METHODS Experimental itch was induced by application of histamine (0.1 mM) v...

Journal: :Molecular Pain 2008
Won-Sik Shim Uhtaek Oh

Itch is one of the major complications of skin diseases. Although there are various substances that induce itch or pruritus, it is evident that histamine is the best known endogenous agent that evokes itch. Even though histamine-induced itch has been studied for some time, the underlying mechanism of itch is just beginning to emerge. Although various downstream signaling pathways of histamine r...

Journal: :Acta dermato-venereologica 2016
Antionette I M van Laarhoven Dietmar J O Ulrich Oliver H Wilder-Smith Nancy E E van Loey Marianne Nieuwenhuis Nic J A van der Wee Andrea W M Evers

A substantial proportion of patients with burn injury develop chronic itch, which can severely affect their quality of life. As found in research on chronic pain, different psychophysiological processes may also play a role in chronic itch, of which central sensitization, conditioned modulation, and attentional processes have been studied most frequently. This study aimed to explore psychophysi...

Journal: :Allergy 2015
V Napadow A Li M L Loggia J Kim I Mawla G Desbordes P C Schalock E A Lerner T N Tran J Ring B R Rosen T J Kaptchuk F Pfab

BACKGROUND Psychological factors are known to significantly modulate itch in patients suffering from chronic itch. Itch is also highly susceptible to both placebo and nocebo (negative placebo) effects. Brain activity likely supports nocebo-induced itch, but is currently unknown. METHODS We collected functional MRI (fMRI) data from atopic dermatitis (AD) patients, in a within-subject design, a...

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