نتایج جستجو برای: kd2 pro

تعداد نتایج: 83994  

Journal: :Chimia 2014
Roger Slavik Daniel Bieri Stjepko Cermak Adrienne Müller Stefanie D Krämer Markus Weber Roger Schibli Simon M Ametamey Linjing Mu

The cannabinoid receptor type 2 (CB2) has a very low expression level in brain tissue under basal conditions, but it is up-regulated in diverse pathological conditions. Two promising lead structures from the literature, N-((3S,5S,7S)-adamantan-1-yl)-8-methoxy-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide and 8-butoxy-N-(2-fluoro-2-phenylethyl)-7-methoxy-2-oxo-1,2-dihydroquinoline-3-carboxam...

[if gte mso 9]> In the present work, the thermal conductivity coefficients of nanoparticle-oil suspensions for two types of carbon nanotubes, single-walled (SWNTs) and multi-walled (MWNTs) carbon nanotubes at 0.1, 0.2 and 0.3 wt.% were measured by a modified transient hot wire method (KD2-pro thermal property meter). Results showed that the thermal conductivity of suspension containing single-...

Journal: :Biological chemistry 2001
B G Díaz S Gross I Assfalg-Machleidt D Pfeiler N Gollmitzer D Gabrijelcic-Geiger M T Stubbs H Fritz E A Auerswald W Machleidt

Within the cystatin superfamily, only kininogen domain 2 (KD2) is able to inhibit mu- and m-calpain. In an attempt to elucidate the structural requirements of cystatins for calpain inhibition, we constructed recombinant hybrids of human stefin B (an intracellular family 1 cystatin) with KD2 and deltaL110 deletion mutants of chicken cystatin-KD2 hybrids. Substitution of the N-terminal contact re...

This study was designed to experimentally measure the thermal and electrical conductivities of Aluminium Nitride/Ethylene Glycol (AlN/EG) nanofluids. Transmission electron microscopy (TEM) was used to characterize the shape of AlN nanoparticles. Nanofluids with different particle volume concentrations of 0.5%, 1%, 2%, 3%, 4%, and 5% were utilized. The thermal and electrical conductivities of the...

Journal: :Journal of Thermal Engineering 2021

Enhanced thermal conductivity of nanofluids has proven importance in enhancing heat transfer for many application. In this study, graphite nanopowder dispersed water at different temperatures was studied experimentally. Stable concentrations (0.2 vol%, 0.5 0.8 1 vol% and 1.5 vol%) are prepared using ultrasonic cleaner by sonicating 3 hour. Thermal measured from temperature 25 to 55 ºC with an i...

Journal: :Asian journal of physical and chemical sciences 2023

This work concerns the technical study of implementation, thermal and mechanical characterization a composite material based on clay plant fibers, in order to meet need for bioclimatic sustainable houses. The objective was find proportions fibers obtain mixture that would give better properties. A properties made thanks KD2 Pro analyzer samples various formulas clay-plant fibers. results obtain...

2017
Lin Zheng Wei Zhang Fei Liang Shuang Lin Xiangyu Jin

The paper presents the different properties of phase change material (PCM) and Microencapsulated phase change material (MEPCM) employed to cold storage/transportation system with a solar-driven cooling cycle. Differential Scanning Calorimeter (DSC) tests have been performed to analyze the materials enthalpy, melting temperature range, and temperature range of solidification. KD2 Pro is used to ...

Journal: :The Journal of biological chemistry 1996
J Bass T Kurose M Pashmforoush D F Steiner

A unique feature of the insulin receptor is that it is dimeric in the absence of ligand. Dimerization of two adjacent transmembrane domain (TMD) alpha helices has been shown to be critical in receptor kinase activation. Moreover, previous work has suggested that the TMD is involved in stabilizing the high-affinity binding site; soluble receptors expressed after simple truncation at the ectodoma...

2017
Joshua D. Eaton Mike P. Williamson

The affinity of epigallocatechin gallate (EGCG) for human serum albumin (HSA) was measured in physiological conditions using NMR and isothermal titration calorimetry (ITC). NMR estimated the Ka (self-dissociation constant) of EGCG as 50 mM. NMR showed two binding events: strong (n1=1.8 ± 0.2; Kd1 =19 ± 12 μM) and weak (n2∼20; Kd2 =40 ± 20 mM). ITC also showed two binding events: strong (n1=2.5 ...

Journal: :Sustainable Energy Technologies and Assessments 2021

The upward energy demand, along with the depletion of conventional sources, demands improved utilization renewable resources. Among all resources, solar is most appropriate alternative to sources owing its inexhaustibility and green property. Solar collectors are devices that convert radiation into heat or energy. However, efficiency collector still not adequate. competent step enhance use nano...

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