نتایج جستجو برای: ketoprofen

تعداد نتایج: 1073  

2012
Katja Mustonen Anneli Niemi Marja Raekallio Mari Heinonen Olli AT Peltoniemi Mari Palviainen Mia Siven Marikki Peltoniemi Outi Vainio

BACKGROUND Ketoprofen is a non-steroidal anti-inflammatory drug which has been widely used for domestic animals. Orally administered racemic ketoprofen has been reported to be absorbed well in pigs, and bioavailability was almost complete. The objectives of this study were to analyze R- and S-ketoprofen concentrations in plasma after oral (PO) and intra muscular (IM) routes of administration, a...

2016
Tiffany Yvonne Loh Philip R. Cohen

Drug-induced photosensitivity reactions are significant adverse effects. Ketoprofen is one of the most common drugs that can cause skin rash in sun-exposed areas. Non-steroidal anti-inflammatory drugs (NSAIDs), such as ketoprofen, are often used for a variety of symptoms, including pain and fever. An understanding of the presentation and clinical course of ketoprofen-induced photosensitivity is...

Journal: :Journal of nephropathology 2013
Dejan Spasovski Arif Latifi Nada Marina Jordan Calovski Irena Kafedziska Gjorgi Božinovski Snežana Percinkova Maja Slaninka-Micevska Trajan Balkanov Beti Dejanova Sonja Alabakovska Svetlana Krstevska-Balkanov Goce Spasovski Dejan Spasovski

BACKGROUND The aim of this study was to determine the effect of initial therapy with some disease modifying antirheumatic drugs (DMARDs) (Methotrexate and Ketoprofen) on glomerular and tubular integrity in patients with Rheumatoid arthritis (RA). OBJECTIVES OBJECTIVES To determine whether there is a change in clinical and laboratory indicators of renal function in course of the follow up o...

Journal: :Journal of Pharmacy and Science 2023

Ketoprofen is a non-steroidal anti-inflammatory compound (NSAID) which has low solubility in water. The aim of this study was to increase the dissolution rate ketoprofen by forming multicomponent ketoprofen-Proline with ratio 1:1, 1:2, and 2:1 using solid state grinding method. Samples were characterized Powder X-Ray Diffractometry (PXRD), Differential Scanning Calorimetry (DSC), Fourier Transf...

2014
Dawood Ahmad Hamdani Aqeel Javeed Muhammad Ashraf Jawad Nazir Aamir Ghafoor

Purpose: To study the immunosuppressant and immunopotentiating effects of ketoprofen on antibodyproducing cells. Methods: Mice were given ketoprofen at doses of 1 mg/kg/day and 5 mg/kg/day for seven days. Similarly polyinosinic–polycytidylic acid (Poly IC) and phosphate buffer saline (PBS) were used as positive and negative control, respectively, for seven days. After seven days, the mice were ...

Journal: :Acta pharmaceutica Nordica 1991
C Larsen B H Jensen H P Olesen

The bioavailability of ketoprofen after oral administration of aqueous solutions of various ketoprofen-dextran ester prodrugs in pigs was assessed. Conjugates derived from dextran fractions in the molecular weight range 10,000-500,000 were employed. Compared to the administration of an oral solution of an equivalent dose of parent ketoprofen, the average absorption fractions for the different p...

Journal: :Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2014
Muhammad Tahir Razi Ibrahim Javed Muhammad Zabta Choudry Muhammad Tariq Khan Noreen Mukhtar

BACKGROUND In different clinical investigations of thrombocytopenia, ketoprofen was found to be the associated cause. Ketoprofen alone or in combination with other therapeutic regimens leads to a decrease in platelet count. Thrombocytopenia due to ketoprofen use can be a threatening condition to the patients who require uncompromised platelet function. OBJECTIVES In order to establish a mecha...

Journal: :Comparative medicine 2007
Thomas G Mast Edwin R Griff

We evaluated ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), as an antinociceptive supplement to chloral hydrate anesthesia in mouse. Effects of ketoprofen on main olfactory bulb (MOB) neuronal spontaneous activity were investigated using extracellular recordings in mouse in vivo. These effects were compared with those of another nociceptive supplement, the mu-opioid agonist buprenor...

Journal: :Postgraduate medical journal 1991
T C Wa M Lawson S H Jackson A Hitoglou-Makedou P Turner

The effects of ketoprofen on frusemide-induced diuresis, natriuresis and renin release were studied in 12 healthy male volunteers. Each received frusemide 40 mg once daily with either ketoprofen 100 mg twice daily or placebo for two periods of 5 days separated by a treatment-free period according to a randomized, double-blind, cross-over study design. Ketoprofen significantly reduced frusemide-...

A. Asghari G. Abedi, H. Hajizadeh S. Hesaraki

The present study was conducted with the aim of comparing the effects of premedication with ketoprofen and midazolam in birds. A total of 24 male pigeons with an approximate weight of 300 g were divided into four equal groups. The control group (Group I) was injected with ketamine alone. Groups II-IV were injected with ketoprofen alone, ketoprofen+ketamine, and midazolam+ketamine, respectively....

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