The postsynaptic membrane of the neuromuscular junction contains a myristoylated 43-kD protein (43k) that is closely associated with the cytoplasmic face of the nicotinic acetylcholine receptor (AChR)-rich plasma membrane. Previously, we described fibroblast cell lines expressing recombinant AChRs. Transfection of these cell lines with 43k was necessary and sufficient for reorganization of AChR...

Recombinant acetylcholine receptors (AChRs) expressed on the surface of cultured fibroblasts become organized into discrete membrane domains when the 43-kD postsynaptic protein (43k) is co-expressed in the same cells (Froehner, S.C., C. W. Luetje, P. B. Scotland, and J. Patrick, 1990. Neuron. 5:403-410; Phillips, W. D., M. C. Kopta, P. Blount, P. D. Gardner, J. H. Steinbach, and J. P. Merlie. 1...

â â â  in the last years, have been accelerated increased the damages of landslides by natural and anthropogenic factors. one of the main solutions to decrease landslide hazards is avoid from prone areas. for this purpose, it is necessary to prepare the landslide susceptibility map. in this research, after field studies in the ilam dam basin, nine factors including slope gradient, aspect, eleva...

This study is a service evaluation of short-term therapeutic effectiveness and progress in therapy for participants seeking help at 42 different counseling centers across the nation. To examine the dose-effect relationship between the number of sessions (dosage) and the therapeutic outcome, 1,698 subjects were monitored through their therapy process as part of a large, nationwide counseling cen...

distinguishing the susceptible areas to landslide using different landslide susceptibility mapping (lsm) models is one of the primitive and basic works to reduce probable damages and reduce risk. the main purpose of this research is the efficiency evaluation of four methods including information value (winf), valuing area accumulation (wa), analytical hierarchy process (ahp), kopta-joshi propos...

In his 1957 Annual Review of Psychology article, Winder defines psychotherapy as an interpersonal relationship characterized by the following attributes (p. 309): (1) at least one of the participants (i.e., therapist) is an expert in human relationships; (2) at least one of the participants (i.e., client) displays intrapersonal or interpersonal adjustment problems; (3) the objective of the rela...

KOPTA DANIEL: Impact of the structure of agricultural production to the fi nancial health of farms. Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013, LXI, No. 7, pp. 2317–2325 The fi rst part of the paper deals with the infl uence of individual commodities on the profi tability and risks of farms. Production structure was given thought share of twelve basic crops in ...

The authors report a meta-analysis of high-quality studies published from 1990–1998 on the efficacy of manualized psychotherapies for depression, panic disorder, and generalized anxiety disorder (GAD) that bear on the clinical utility and external validity of empirically supported therapies. The results suggest that a substantial proportion of patients with panic improve and remain improved; th...