We revisit the 3D Cauchy problem of compressible heat-conducting magnetohydrodynamic equations with vacuum as far field density. By delicate energy method, we derive global existence and uniqueness strong solutions provided that (??0?L?+1)[??0?L3+(??0?L?+1)2(??0u0?L22+?b0?L22)][??u0?L22+(??0?L?+1)(??0E0?L22+??b0?L22)] is properly small. In particular, smallness condition independent any norms i...

Pseudomonas is a complex genus with increasing numbers of new species. Recently, we isolated sp. strain L22-9, which showed antifungal activity against several fungal phytopathogens. Here, report the whole genome sequence L22-9. Genomic analysis revealed that L22-9 contains one circular DNA chromosome 6,730,360 bp length 60.9% GC content. Bioinformatics identified gene clusters in synthesize an...

The Epstein-Barr virus (EBV)-encoded RNAs, EBER-1 and EBER-2, are highly abundant noncoding nuclear RNAs expressed during all forms of EBV latency. The EBERs have been shown to impart significant tumorigenic potential upon EBV-negative Burkitt lymphoma (BL) cells and to contribute to the growth potential of other B-cell lymphoma-, gastric carcinoma-, and nasopharyngeal carcinoma-derived cell li...

To identify proteins that can bind the 3* untranslated region (UTR) of hepatitis C virus (HCV) we screened human cDNA libraries using the Saccharomyces cerevisiae three-hybrid system. Screening with an RNA sequence derived from the 3*-terminal 98 nucleotides (3*X region) of an infectious clone of HCV (H77c) yielded clones of human ribosomal proteins L22, L3, S3, and mL3, a mitochondrial homolog...

To identify proteins that can bind the 3' untranslated region (UTR) of hepatitis C virus (HCV) we screened human cDNA libraries using the Saccharomyces cerevisiae three-hybrid system. Screening with an RNA sequence derived from the 3'-terminal 98 nucleotides (3'X region) of an infectious clone of HCV (H77c) yielded clones of human ribosomal proteins L22, L3, S3, and mL3, a mitochondrial homolog...

OBJECTIVES The aim of this study was to characterize the mechanism of resistance to macrolides and streptogramins of a Streptococcus pneumoniae strain isolated from blood cultures in an 80-year-old patient suffering from severe pneumonia unsuccessfully treated with pristinamycin. METHODS Resistance genes erm(B) and mef(A) were searched for by PCR. Portions of genes for domains V and II of the...

L4 and L22, proteins of the large ribosomal subunit, contain globular surface domains and elongated 'tentacles' that reach into the core of the large subunit to form part of the lining of the peptide exit tunnel. Mutations in the tentacles of L4 and L22 confer macrolide resistance in a variety of pathogenic and non-pathogenic bacteria. In Escherichia coli, a Lys-to-Glu mutation in L4 and a thre...

The ribosomal protein L22 is a component of the 60S eukaryotic ribosomal subunit. As an RNA-binding protein, it has been shown to interact with both cellular and viral RNAs including 28S rRNA and the Epstein-Barr virus encoded RNA, EBER-1. L22 is localized to the cell nucleus where it accumulates in nucleoli. Although previous studies demonstrated that a specific amino acid sequence is required...

We give a comprehensive theoretical characterization of a nonparametric estimator for the L2 divergence between two continuous distributions. We first bound the rate of convergence of our estimator, showing that it is √ n-consistent provided the densities are sufficiently smooth. In this smooth regime, we then show that our estimator is asymptotically normal, construct asymptotic confidence int...

Amino acids are polymerized into peptides in the peptidyl transferase center of the ribosome. The nascent peptides then pass through the exit tunnel before they reach the extraribosomal environment. A number of nascent peptides interact with the exit tunnel and stall elongation at specific sites within their peptide chain. Several mutational changes in RNA and protein components of the ribosome...