In recent years, several radiopharmaceuticals have been developed for imaging regional cerebral blood flow (rCBF) such as 75Se labelled PIPSE and MOSE, ²º¹TI labelled DDC and 99mTc labelled HMPAO. HMPAO with two asymmetric carbon atoms (At the 3 and 9 positions), produces d,1 and meso isomers, only one of which is retained in the brain. Rapid intracellular conversion of 99mTc-d,1-HMPAO to...

Discovery of 13C NMR and its application in the biosynthetic pathways prompted the synthesis of several 13C labelled precursors. To investigate the metabolism of phenyllactic acid in the Solanaceae family, the double labelled acid was synthesized from barium carbonate (13C) and sodium syanide (13C)

After exposure to 2 mg/L (14)C-labelled KRM-1648 (a new broad-spectrum benzoxazinorifamycin antibiotic) for 5 min, a steady-state concentration of 31.3 +/- 3 ng/mg cells KRM-1648 and 12. 6 +/- 0.3 ng/mg cells KRM-1648 was accumulated by wild-type antibiotic-susceptible Mycobacterium aurum (A+) and Mycobacterium tuberculosis (H37Rv), respectively. However, 2 mg/L KRM-1648 was bactericidal for M....

Non-invasive in vivo molecular imaging using radionuclides is based on the Radiotracer Principle of G. von Hevesy and the magic bullet concept by Ehrlich (1990). Both principles require administration of a radioactive tracer (a molecule labelled with a radioactive isotope which when injected into a living object can be traced by external radiation detection devices) and require that the quantit...

context inherited and sporadic medullary thyroid cancer (mtc) is an uncommon and medically challenging malignancy. even if the extent of initial surgery is deemed adequate, the recurrence rate remains high, up to 50% in most series. measurement of serum calcitonin is important in the follow-up of patients with mtc, and reliably reflects the existence of the disease. evidence acquisition there i...

Let G be a (p, q) graph. Let k be an integer with 2 ≤ k ≤ p and f from V (G) to the set {1, 2, . . . , k} be a map. For each edge uv, assign the label |f(u) − f(v)|. The function f is called a k-difference cordial labeling of G if |νf (i) − vf (j)| ≤ 1 and |ef (0) − ef (1)| ≤ 1 where vf (x) denotes the number of vertices labelled with x (x ∈ {1, 2 . . . , k}), ef (1) and ef (0) respectively den...

discovery of 13c nmr and its application in the biosynthetic pathways prompted the synthesis of several 13c labelled precursors. to investigate the metabolism of phenyllactic acid in the solanaceae family, the double labelled acid was synthesized from barium carbonate (13c) and sodium syanide (13c)

cystic hydatid disease is caused by cystic larval (metacestode) stages of echinococcus granulosus. this parasite can potentially occur all over the world especially in mediterranean and middle east countries and some parts of africa, latin america and china which have major foci of human infections. the cyst wall of metacestodes consists of inner, middle and external layers. to date, little att...