abstract   background: squamous cell carcinoma (scc) constitutes the main oral malignancy . parallel to better understanding of molecular and genetic patterns of tumor behavior, more precise correlation of tumor markers such as epidermal growth factor (egf) and laminin-5 are sought to estimate macroscopic and microscopic tumor status .   methods: we conducted a cross-sectional study collecting ...

In linear IgA bullous dermatosis (LABD) caused by IgA-class autoantibodies against proteins in the basement membrane zone (BMZ), IgG deposition along BMZ can be observed, and such cases have been recently referred to as IgA/IgG (LAGBD). Our patient presented with a history of oral nasopharyngeal ulcers followed development tense bullae over chest, back extremities, arranged an annular pattern c...

Biomaterial bridging provides physical substrates to guide axonal growth across the lesion. To achieve efficient directional guidance, combinatory strategies using permissive matrix, cells and trophic factors are necessary. In present study, we evaluated effect of poly (acrylonitrile-co-vinyl chloride) guidance channels filled by different densities laminin-precoated unidirectional polypropylen...

breakthrough bleeding (btb) is the cause of 50% of discontinuations of use by long-acting progestogen-only contraceptive users. btb appears to be associated with capillaries of abnormal morphology and fragility. disturbances in vessels integrity, intercellular junctions or alteration of the basement membrane (bm) composition has been proposed to contribute toward the fragility of these capillar...

Polyclonal antisera were made against biochemically purified laminin receptor protein as well as against synthetic peptides deduced from a complementary DNA clone corresponding to the COOH-terminal end of the laminin receptor (U.M. Wewer et al., Proc. Natl. Acad. Sci. USA, 83: 7137-7141, 1986). These antisera were used to study the potential role of laminin receptor in laminin-mediated attachme...

The characteristics of a material’s surface are extremely important when considering their interactions with biological species. Despite chemistry playing critical role in mediating the responses cells, there remains no single rule which dictates absolute performance; this is particularly challenging response differing cell types to range materials. Here, we highlight functional behavior neural...