A reliable, relatively simple method for isolation and quantification of disaturated lecithins is described. In rabbit lung, 34% of the lecithins were disaturated, in alveolar macrophages, 19%. More than 95% of the fatty acids of the disaturated lecithins from lung and alveolar macrophages was palmitic. Hence, the disaturated lecithins from these sources were essentially all dipalmitoyl lecithi...

Using the data reported previously by Moriya and Kanoh, the metabolic turnover of rat lung lecithins was calculated on the basis of the new assumption that the formation rate (Va) of lecithins from diacylglycerols did not equal the disappearance rate (Vb) of lecithins because of the presence of precursors other than diacylglycerols. The ratio of Va/Vb was almost the same in dienoic lecithin as ...

The investigation of the structure of the lecithins and cephalins (phosphatidylethanolamines) from natural sources gave rise to the question, whether the phosphoric acid in these substances is attached to the (Yor P-carbon atom of the glycerol moiety. Since the acid and alkaline hydrolysis of natural lecithins yielded mixtures of CYand p-glycerophosphoric acid (GPA), it was assumed that they ex...

We determined the distribution of lecithin molecular species between vesicles and mixed micelles in cholesterol super-saturated model biles (molar taurocholate-lecithin-cholesterol ratio 67:23:10, 3 g/dl, 0.15 M NaCl, pH approximately 6-7) that contained equimolar synthetic lecithin mixtures or egg yolk or soybean lecithins. After apparent equilibration (48 h), biles were fractionated by Supero...

The work on liver lecithins by Levene and Ingvaldsen’ and by Levene and Simms,z has shown the existence of lecithins which are distinguished from one another by the nature of their unsaturated fatty acids. There were isolated from liver lecithin, two unsaturated fatty acids, oleic and arachidonic, as well as two saturated acids, palmitic and stearic. Hence on the basis of the present findings i...

The effects of four different canola lecithins applied at proportions of 30 g fatty acid kgÿ1 diet were compared with diets containing either no additional lipid or the same amount of fatty acids from canola seed, pure canola oil and deoiled soy lecithin, respectively. Four types of canola lecithin with increasing dispersibility in water were used: raw; deoiled; deoiled/hydrolysed; and hydrolys...

The lecithins of rat liver are resolved into three fractions by chromatography on a thin layer of silica gel impregnated with silver nitrate. Each of these fractions is placed in a small column containing a cation-exchange resin, and the lecithins are eluted free from silver nitrate. Recoveries average 96%.

In view of the biological significance of the lecithins a.nd of the fact that t;hey have been known to the chemist for a hundred years (l), it is rather surprising that there should still remain doubts concerning the position of the phosphoric acid. Until recently it has been assumed by most workers that lecithins could be hydrolyzed chemically without causing a change in the position of the ph...

The possibility that naturally occurring lecithins may contain 1 molecule each of a saturated and an unsaturated fatty acid has never been shown. The data of Levene and Rolf (1) on the brominated lecithins from liver could be interpreted as indirect support for this theory. However, the evidence provided by Contardi and Latzer (2), Snider and Bloor (3), and Sinclair (4) on the fatty acid compos...