leishmania infantum, an etiologic agent of zoonotic visceral leishmaniasis (vl), is spreading in iran. dogs are the main reservoirs but l.infantum has been detected in jackals, foxes and wild rodents too. despite high number of rodents in the world, the exact role of them in epidemiology of vl is not clear. in recent years the number of sporadic cases of dogs and humans vl has been increased in...

Leishmania infantum, an etiologic agent of zoonotic visceral leishmaniasis (VL), is spreading in Iran. Dogs are the main reservoirs but L.infantum has been detected in jackals, foxes and wild rodents too. Despite high number of rodents in the world, the exact role of them in epidemiology of VL is not clear. In recent years the number of sporadic cases of dogs and humans VL has been increased in...

A leishmaniose cutânea causada por Leishmania major é uma zoonose pelo protozoário do gênero Leishmania. doença caracterizada surgimento de lesões cutâneas pequenas, forma arredondada, profunda, avermelhada que podem crescer progressivamente.

Previous hypotheses of Leishmania evolution are undermined by limitations in the phylogenetic reconstruction method employed or due to the omission of key parasites. In this experiment, sequences of the gene encoding the DNA polymerase alpha catalytic polypeptide (POLA) were analysed phylogenetically in combination with those encoding the RNA polymerase II largest subunit gene (RPOIILS) to infe...

Leishmaniases are endemic zoonoses in the State of Mato Grosso do Sul. Their etiological agents in this region of Brazil are Leishmania (Leishmania) chagasi, Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis. The polymerase chain reaction (PCR) is a tool with high specificity and sensitivity for identifying Leishmania species. This study examined 39 cryopreserved isolate...

New therapeutic alternatives against leishmaniasis remain a priority. The activity of azithromycin against Leishmania (Leishmania) major has been previously demonstrated. Different responses among species of Leishmania make species-specific drug screening necessary. The activity of azithromycin against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis was evaluated in go...

Background: Lipophosphoglycan 3 (LPG3) is required for the LPG assembly, a well known virulent molecule. In this study, the LPG3 gene of the lizard and mammalian Leishmania species were cloned and sequenced. A three-dimensional structure (3D) for the target sequence was also predicted by comparative (homology) modeling. Materials and Methods: An optimization PCR amplification was performed o...

Mexico is considered endemic for Leishmania; recent reports indicate autochthonous human and canine leishmaniasis caused by Leishmania mexicana in Sinaloa state. Lutzomyia sand fly are the primary vector of parasite, although no records phlebotomine vectors exist from Sinaloa. Other hematophagous dipterans, like Culicoides, could represent possible absence phlebotomines. The known distribution ...