background: infertility is a problem concerning 10-15% of the individuals in the fertile period. this study investigated effects of proinflammatory factors as well as lipid hydroperoxides (lpo) levels upon in vitro fertilization (ivf) success. materials and methods: in this prospective, non-randomized, controlled clinical study, sera obtained from 26 fertile (group-1), 26 infertile women before...

background: the association between lipid peroxidation biomarkers and adipocytokines is hypothesized in preeclampsia but little is known about it. objective: the present study was undertaken to determine the association of lipid peroxidation biomarkers measured by the levels of 8-isoprostane and malondialdehyde with adipocytokines leptin and adiponectin in maternal serum of preeclamptic women. ...

OBJECTIVE Leptin, a hormone present in breast milk, is involved in energy regulation and metabolism. The purpose of this investigation was to determine whether leptin is present in either preterm breast milk (PBM) or preterm formula (PF). The effects of delivery methods and pasteurization on leptin levels also were evaluated. METHODS PBM samples were obtained from 29 mothers who delivered inf...

The mechanisms of the increased serum leptin in response to feeding are poorly understood. Therefore, we used metabolic labeling to directly assess leptin biosynthesis, secretion, and turnover in adipose tissue from 14 h-starved compared with fed 12-14 week old rats. Starvation decreased serum leptin (-47 +/- 7%), adipose tissue leptin content (-32 +/- 5%), and leptin secretion during 3 h of in...

Background Obesity is a medical problem in survivors of childhood acute lymphoblastic leukemia. Obesity is associated with many complications, so it is important to investigate the respective etiology. Leptin is a protein synthesized in the fatty tissue and is effective in the control of obesity. Survey of leptin in acute lymphoblastic leukemia (ALL) survivors could be helpful in controlling ob...

Elevated plasma leptin levels, or hyperleptinemia, have been demonstrated to correlate with metabolic syndrome markers, including obesity, and may be an independent risk factor for the development of cardiovascular disease. In this paper, we use cardiac models study possible effects hyperleptinemia on electrophysiological properties cardiomyocytes arrhythmias. We modified parameters improved Ga...

the prevalence of atopic dermatitis (ad) and obesity have been increasing considerably in korean school-children. ad is a chronic pruritic recurrent inflammatory skin disorder. leptin is secreted by adipocytes which has been suggested to be immunologically active; however, their role in ad has not yet been well understood. a total of 227 subjects out of 2,109 elementary school children were def...