نتایج جستجو برای: leptin receptor

تعداد نتایج: 604488  

Journal: :gene, cell and tissue 0
saeed khosropour department of medical biochemistry, hamedan university of medical sciences, hamedan, ir iran maryam shojaee department of biology, payam noor university of mashhad, mashhad, ir iran; department of biology, payam noor university of mashhad, mashhad, ir iran peyman lotfi department of biology, science and research branch, islamic azad university, tehran, ir iran

Karimzadeh M, Parham A

Background: Many hormones are involved in the regulation of reproduction. Leptin hormone which is mainly secreted by adipose tissue plays an important role in energy homeostasis and reproduction. It seems that leptin is an important linkage between body metabolism and reproductive system. Moreover, it has been shown that leptin and leptin receptor express in reproductive organs of some species....

Journal: :journal of research in medical sciences 0
ghorban mohammadzadeh mohammad-ali ghaffari ahmmad bafandeh seyed-mohammad hosseini

background: leptin plays a key role in the regulation of energy expenditure and is known to circulate in both free and bound forms. soluble leptin receptor (sob-r) is a unique circulating form of leptin receptor that can bind to leptin. leptin and leptin receptor have been implicated in processes leading to breast cancer initiation and progression. our study was aimed to investigate the relatio...

Background: Leptin, the product of the obesity (ob) gene, acts as a signaling adipokine for modulating food intake, energy metabolism and reproductive functions in mammals. Leptin’s effects on the reproductive system at various levels of the hypothalamic-pituitary-gonadal axis have been established. Moreover, the direct and local effect of leptin on bovine oocyte maturation and corpus luteum fu...

ژورنال: Medical Laboratory Journal 2014
Esmaeili, R, Hassanzadeh, T,

Abstract Background and Objective: Metabolic syndrome called a cluster of several metabolic disorders is associated with increased risk of cardiovascular diseases. Genetic differences in leptin receptor gene are related with the concentration and activity of leptin in that these discrepancies can influence lipid levels. We aimed to determine the association between the leptin receptor gene p...

M. Roostaei-Ali Mehr, R. Motamedi-Mojdehi R. Rajabi-Toustani

Leptin is secreted mainly by fat, which is involved in energy metabolism and reproduction. Leptin and itsreceptor (Ob-R) have been detected in human spermatozoa and testis, thus it can be concluded leptin involves in male physiology. The goal of this study was determination of the presence of leptin receptor mRNA in the ram testis, epididymis and spermatozoa by reverse transcription polymerase ...

Ahmmad Bafandeh Ghorban Mohammadzadeh, Mohammad-Ali Ghaffari, Sayed-Mohammad Hosseini

Objective(s):Leptin receptor (LEPR) is a member of the class I cytokine receptor super-family that is known implicated in the initiation and progression of breast cancer. We have investigated the effect of Q223R polymorphism on the breast cancer susceptibly in a sample of Iranian subjects. Materials and Methods:We utilized a polymerase chain reaction (PCR) restriction fragment length polymorphi...

Journal: :iranian journal of veterinary research 2013
m. roostaei-ali mehr r. rajabi-toustani r. motamedi-mojdehi

leptin is secreted mainly by fat, which is involved in energy metabolism and reproduction. leptin and itsreceptor (ob-r) have been detected in human spermatozoa and testis, thus it can be concluded leptin involves in male physiology. the goal of this study was determination of the presence of leptin receptor mrna in the ram testis, epididymis and spermatozoa by reverse transcription polymerase ...

Introduction: A specific role of dopamine D2 receptor signaling of midbrain and hypothalamic dopaminergic systems has not been yet identified in energy homeostasis. Here, we investigated effects of intra-ventromedial hypothalamus (VMH) administration of the D2 receptor agonist (quinpirole) and antagonist (sulpiride) on plasma leptin and glucose levels in fasted rats. Methods: A guide cannul...

Osteoporosis is a systemic skeletal disease and there is a close relationship between the sympathetic nervous system (SNS) and bone metabolism. Leptin has been shown to regulate bone formation and bone resorption via the SNS. However, the effect of SNS on leptin signaling has not been clearly understood. In the present study, we studied the effect of propranolol on ovariectomy-induced osteoporo...

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