in order to evaluate the effect of different mechanical treatments (application of sulphuric acid, boiling water and flooding) on seed dormancy breaking of licorice, an experiment was carried out in randomized complete block design in 2012. moreover, a factorial scheme in rcbd was performed to assess the application of giberalic acid and potassium nitrate treatment as well as stratification and...

laboratory experiments were performed to determine the effect of various scarification treatments at four temperature regimes on germination of licorice seeds . a randomized complete block design with four replications was used. germination counts were made every day for 2 weeks. at 50c, none of the chemically and mechanically scarified and non scarified seeds germinated. at 15, 25, and 350...

In traditional Chinese medicine (TCM), licorice is usually processed with honey and traditionally used in decoction form. However, the influence of honey-roasting on the main pharmacological activities and the water-soluble active constituents of licorice has not been reported. The aim of the present study is to determine whether honey-roasting can modify the main pharmacological activities and...

Licorice, the oldest Chinese traditional medicine, is widely used in the treatment of human diseases. Due to the deficiency of wild resource, selecting and breeding becomes a key issue to expanding the supply of licorice. Spaceflight technology will become a new method for medicinal plants. The aim of this study was to investigate the effect of spaceflight on the components and anti-inflammator...

A 49-year-old female physician presented with peripheral edema, weight gain and relative hypertension caused by the consumption of licorice candy cigars containing glycyrrhizic acid (GZA) found in natural licorice extract. Although the patient's response to GZA resolved spontaneously, emergency physician awareness of the toxic effects of natural licorice extract may avert symptom progression in...

Licorice, Glycyrrhiza glabra Linn., is one of herbal medicines widely used for various purposes, including as a sweetener and for gastric ulcer treatment. However, environmental destruction due to the harvesting of wild licorice is becoming a serious problem. We cultured licorice in a hydroponic system to examine the relation between the concentration of nutritional solution applied and glycyrr...

Licorice is commonly used as a cure for digestive disorders and as a detoxification agent in East Asia. This study investigated the protective effect of licorice water extract against cadmium (CdCl(2), Cd)-induced liver toxicity in rats. To induce acute toxicity, Cd (4 mg/kg body weight) was dissolved in normal saline and intravenously (i.v.) injected into rats. The rats then received either a ...

BACKGROUND Our previous study suggested that licorice has anti-inflammatory activity in lipopolysaccharide-stimulated microglial cells and anti-oxidative activity in tert-butyl hydroperoxide-induced oxidative liver damage. In this study, we evaluated the effect of licorice on chronic alcohol-induced fatty liver injury mediated by inflammation and oxidative stress. METHODS Raw licorice was ext...

Licorice ingestion, as well as mutations in the HSD11B2 gene, inhibits 11β-hydroxysteroid dehydrogenase type 2 (11βHSD2) enzyme activity, causing the syndrome of apparent mineral corticoid excess (AME). However, the combined effect of licorice ingestion and an HSD11B2 mutation has never been reported, until now. In this study, we demonstrated that licorice ingestion can produce overt hypertensi...

BACKGROUND/OBJECTIVE Licorice has been shown to possess cancer chemopreventive effects. However, glycyrrhizin, a major component in licorice, was found to interfere with steroid metabolism and cause edema and hypertension. The roasting process of licorice modifies the chemical composition and converts glycyrrhizin to glycyrrhetinic acid. The purpose of this study was to examine the anti-carcino...