In Japan, mass screening tests on newborns for Cretinism have been performed since 1984, Cretinism is a very rare condition. We report the clinical course and complications of longitudinal thyroid hormone replacement therapy (liothyronine sodium: T3) of two women with Cretinism and ectopic thyroid gland for the past 33 years until 2001. They were born in April 1951 (Case 1) and in January 1952 ...

the study on biochemical changes in brain tissue indicates that there are considerable variations in metabolism of energy in this tissue within the first three weeks of life. this phenomenon coincides with the increase of brain energy during that period of life. there are, indeed, various factors, involved in the changing process. hormones and thyroid hormones in particular are of the most impo...

OBJECTIVES The present study assessed the changes in functional, biochemical, and echocardiographic measures following long-term liothyronine therapy in heart failure (HF) patients with low-triiodothyronine (T3) syndrome (LT3S). METHODS In the present placebo-controlled, double-blind study, adult patients with clinically stable New York Heart Association functional class I-III systolic HF and...

CONTEXT Combined infusion of levothyroxine plus liothyronine, as opposed to levothyroxine alone, is the only way of restoring the concentrations of circulating TSH, T4, and T3 as well as those of both T4 and T3 in all tissues of thyroidectomized rats. Considering the substantial differences in thyroid hormone secretion, transport, and metabolism between rats and humans, whether or not combined ...

Objective. Analyzing and managing pre-eclampsia-like syndrome due to severe hypothyroidism. Methods. Presentation of a case of severe hypothyroidism due to Hashimoto's syndrome, associated with a severe early-onset preeclampsia-like syndrome, managed in our Gynecology Department. Results. Severe pre-eclampsia led to miscarriage at 24 weeks of gestational age in a 42-year-old woman, although we ...

Data from National Health and Nutrition Examination Survey (NHANES 1999-2002) reveals 3.7% prevalence of hypothyroidism in the general population [1]. 10.3 million People or 4.6% of those surveyed reported use of thyroid hormones (levothyroxine, liothyronine, or desiccated thyroid) [1]. Desiccated Thyroid Extract (DTE) of animal origin has been used to treat hypothyroidism since 1892 [2,3]. Sev...

introduction: patients administered with a therapeutic dose of 131i for thyroid cancer treatment are potential sources of unacceptably high radiation exposure to other individuals, particularly the patient's immediate family members. the aim of this study is to investigate effects of early liothyronine consumption after radio-iodine therapy on accumulated dose and exposure rate in patients with...