an 11-year-old female patient with autoimmune hepatitis (aih) was referred to our rheumatology clinic due to her current musculoskeletal manifestations. the patient had been diagnosed with aih 3 months previously, based on jaundice and impaired liver function tests, and she had been treated with low-dose prednisolone and azathioprine. she presented with malaise, arthritis, a malar rash on the f...

chronic liver diseases in children is the result of many different diseases including: metabolic, genetic, infectious, toxic and idiopathic causes. this was a case series study on 133 infants and children with age range 6 month to 12 years old, who presented clinically with manifestation of chronic liver disease and were admitted to children hospital medical center from year 1999 to 2000. in th...

aim : the aim of this study was to review our experience with gestations in autoimmune hepatitis patients. background : there are only limited data describing pregnancy in patients with autoimmune hepatitis. patients and methods : retrospective analysis of pregnancies with autoimmune hepatitis followed in centro hospitalar do porto, portugal in the last ten years. results : we reported nine pre...

post-transplant lymphoproliferative disorder is a lymphocyte proliferating disease, usually of b cell origin, and rarely of t cell. involvement of liver itself in liver transplant recipients as the primary organ is not common. herein we report our experience in two patients who primarily presented in the allografted liver, both of whom were promptly diagnosed after liver biopsy and treated succ...

chronic anemia is common in liver cirrhosis. in this setting the pathogenesis of anemia is complex and multifactorial. spur cell anemia is a serious disorder in cirrhotic patients associated with poor prognosis. liver transplantation constitutes the only therapeutic tool. we report a case of  a severe spur cell anemia in alcoholic liver cirrhosis. in the attempt to investigate the origin of the...

In liver disorder, prothrombin time (PT) is elevated, and fibrinogen level decreased which are considered predictors of increased bleeding risk. We aimed at determining whether increased PT and fibrinogen value reflect the haemostatic potential and bleeding risk in patients with liver disorder. The study comprises a total of 135 subjects including patients with liver disorder (n=75) and healthy...

liver injury occurs with many drugs; therefore, a thorough work up is important for establishing the diagnosis. we report a case of trifluoperazine-induced cholestatic jaundice. a 44-year old male with schizoaffective disorder developed an increase in liver enzymes and jaundice after starting treatment with trifluoperazine. workup for other potential etiologies was negative.

Hepatic encephalopathy is a disorder in which the function of brain deteriorates because toxic substances accumulate blood, would normally be removed by liver. Substances absorbed into bloodstream from intestine pass through liver, where toxins are removed. In hepatic encephalopathy, poisons not removed, liver impaired. Additionally, connections made between portal system and general circulatio...