background : retakes of intra oral radiographs happen frequently in dental practice although radiographic courses train dental students in consecutive semesters. to reduce the patient exposure as much as possible it is mandatory to reduce the number of retakes both in radiology clinics and educational centers. materials and methods : 3188 periapical radiographs taken by bisect-angle technique w...

Over the past decade, cross-docking has emerged as an important material handling technology in transportation. A variation of the well-known Vehicle Routing Problem (VRP), the Vehicle Routing Problem with Cross-Docking (VRPCD) arises in a number of logistics planning contexts. This paper addresses the VRPCD, where a set of homogeneous vehicles are used to transport products from the suppliers ...

Chemical cross-links identified by mass spectrometry generate distance restraints that reveal low-resolution structural information on proteins and protein complexes. The technology to reliably generate such data has become mature and robust enough to shift the focus to the question of how these distance restraints can be best integrated into molecular modeling calculations. Here, we introduce ...

So far, many types of location models have been developed to find optimal spatial patterns according to different spatial metrics such as cost, coverage and availability.  The initial focus of these models is on the location availability of service providers and demand estimates, and some of these models are within the framework of multi-objective programming models.  After the advent of scienc...

This paper presents a three-level supply chain model which includes single supplier, several distribution centers and sets of retailers. For this purpose, by adopting the queuing approach, a mixed nonlinear integer programming model is formulated. The proposed model follows minimizing the total cost of the system by determining: 1) the number and location of distribution centers between candida...

With the knowledge accumulated from participating the first cross-docking network development, this paper summarizes the key planning and modeling issues for the crossdocking operations of a large supermarket retail chain in Taiwan. The insights gained from this study can aid large retail chains to better plan their cross-docking operations.

We have determined the three-dimensional structure of the protein complex between latexin and carboxypeptidase A using a combination of chemical cross-linking, mass spectrometry and molecular docking. The locations of three intermolecular cross-links were identified using mass spectrometry and these constraints were used in combination with a speed-optimised docking algorithm allowing us to eva...