In visual change detection tasks, providing a cue to the change location concurrent with the test image (post-cue) can improve performance, suggesting that, without a cue, not all encoded representations are automatically accessed. Our studies examined the possibility that post-cues can encourage the retrieval of representations stored in long-term memory (LTM). Participants detected changes in...

The standard LSTM, although it succeeds in the modeling long-range dependences, suffers from a highly complex structure that can be simplified through modifications to its gate units. This paper was to perform an empirical comparison between the standard LSTM and three new simplified variants that were obtained by eliminating input signal, bias and hidden unit signal from individual gates, on t...

One way to prioritize limited mental resources for perception is to take into account the familiarity of an object to the perceiver. But does an objects' familiarity influence perception only after an object's shape has been determined, or does it influence the decision of which edges are considered part of that object? Here we compare the influence of target familiarity on whole-object masking...

Historically, psychologists and neuroscientists have distinguished between processes supporting memory for events across retention delays of several seconds (short-term memory, STM), and those supporting memory for events across longer retention delays of minutes or more (long-term memory, LTM). Dissociations reported in some neuropsychological studies have contributed to a popular view that th...

Background & Aims: Diabetes mellitus is a chronic metabolic disorder that in the long-term is accompanied with deficits in learning, memory, and cognitive skills. Due to the existing evidence regarding the anti-diabetic potential of acetyl-L-carnitine (ALC), the effect of its long-term administration on learning and spatial memory deficits was investigated in diabetic rats. Methods: In this exp...

When an experience is encrypted into a long-lasting memory, it is believed that specific sets of neurons in the brain of the animal undergo changes including the strengthening of preexisting synapses and the growth and maintenance of new synaptic connections. These activity-dependent synaptic changes appear to require the coordination of a variety of cellular processes in spatially separated ce...

The distinguishability between working memory (WM) and long-term memory has been a frequent and long-lasting source of debate in the literature. One recent method of identifying the relationship between the two systems has been to consider the influence of long-term memory effects, such as the levels-of-processing (LoP) effect, in WM. However, the few studies that have examined the LoP effect i...

De novo protein synthesis and transcription are necessary for the expression of long-lasting synaptic potentiation [long-term potentiation (LTP)] in hippocampal area CA1 and for the consolidation of long-term memory. The stability of LTP and its longevity require macromolecular synthesis at later stages, but a specific role for early protein synthesis has not been identified. Using electrophysi...