In recent years, there is a lot of interest in synthesis of nanostructures as carriers for drug delivery.These structures are considered as a highly effective drug delivery system due to controlling drugrelease, protecting the pharmaceutical molecule, and environmentally friendly. In this study, thesynthesis of chitosan nanoparticles was carried out by chemical method. The nan...

This paper considers the economic lot and delivery scheduling problem in a two-echelon supply chains, where a single supplier produces multiple components on a flexible flow line (FFL) and delivers them directly to an assembly facility (AF). The objective is to determine a cyclic schedule that minimizes the sum of transportation, setup and inventory holding costs per unit time without shortage....

Background and Objectives: The Increase of unnecessary caesarean sections has become one of the serious concerns in some health systems. One of the seven packages of the health Reform Plan that was sent to all Iranian medical universities in 2014 was the "Promoting Natural Delivery (vaginal births)," It emphasized the need to reduce cesarean delivery and promot...

Supply chain is an accepted way of remaining in the competition in today's rapidly changing market. This paper presents a coordinated seller-buyer supply chain model in two stages, which is called Joint Economic Lot Sizing (JELS) in literature. The delivery activities in the supply chain consist of a single raw material. We assume that the delivery lead time is stochastic and follows an exponen...

preterm birth means the birth before thirty seven week of pregnancy that causes a lot of complications for the baby. variety factors are suggested to be involved in disease. in this study, we decided to evaluate haptoglobin (hp) phenotypes association with clinical features of patients suffered from premature delivery to understand better the possible correlation of genetic and clinical feature...

the problem of designing a set of routes with minimum cost to serve a collection of customers with a fleet of vehicles is a fundamental challenge when the number of customers to be dropped or picked up is not known during the planning horizon. the purpose of this paper is to develop a vehicle routing problem (vrp) model that addresses stochastic simultaneous pickup and delivery in the urban pub...

Supply chain management (SCM) addresses the management of materials and information across the entire chain from suppliers to producers, distributors, retailers, and customer. The theory of supply chain management suggests that lead time reduction is a pioneer to the use of market mediation to reduce transaction uncertainty in the chain, which can be conceptualized as the primary goal of supply...