methods this randomized, crossover study with parallel design was conducted in 45 patients who required maintenance hemodialysis due to end-stage renal failure. four patients with known bleeding disorders, receiving anticoagulant drugs and receiving drugs which could affect heparin activity were excluded. all patients were randomly assigned to receive either enoxaparin sodium (0.7 mg/kg) or sta...

background: this study was designed to examine a unique and low dose use of intravenous enoxaparin in elective percutaneous coronary intervention (pci) that would be applicable to an unselected population regardless of age, weight, and renal function. there is limited experience in anticoagulation using intravenous low-molecular-weight heparin in pci. methods: a total of 100 consecutive patient...

background: low molecular weight heparin (lmwh) is used for the treatment and prevention of coagulative disorders. few patients receiving therapeutic doses of lmwh develop major hemorrhage. currently there are few reports in the literature on acute overdose on adults.  in this study, clinical profile, treatment and outcome of 21 patients who acutely overdosed enoxaparin are described. methods: ...

low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (lmwh-isl-sln) was developed for injective application. the morphological observation, particle diameter and zeta potential of lmwh-isl-sln were characterized using transmission electron microscopy (tem) and a malvern zetasizer. its entrapment efficiency (ee) and drug loading (dl) were determined by ultracen...

objective: to determine the incidence of deep vein thrombosis (dvt) in patients undergoing spinal surgeries receiving prophylactic doses of deltaparin in a single center in central iran. method: this cross-sectional study was conducted in shariatee hospital of isfahan during a 12-month period. we included all the patients undergoing elective spinal surgeries in our center during the study perio...

  Background: Low molecular weight heparin (LMWH) is used for the treatment and prevention of coagulative disorders. Few patients receiving therapeutic doses of LMWH develop major hemorrhage. Currently there are few reports in the literature on acute overdose on adults.  In this study, clinical profile, treatment and outcome of 21 patients who acutely overdosed enoxaparin are described. Method...