Background: A big variety in blood group distribution can be seen in some geographic regions, as well as, in some ethnic and socioeconomic groups. Blood groups are, in fact, defined as surface antigens on the erythrocyte cell membrane, and the distribution of the blood groups varies in different regions of the world. Aim: The aim of our study was to investigate blood group distribution (ABO,RhD...

Cytochrome P450 2D6 (CYP2D6) is an enzyme of great importance for the metabolism of clinically used drugs. More than 100 variants of the CYP2D6 gene have been identified so far. The aim of this study was to investigate the allele distribution of CYP2D6 gene variants in 100 individuals of each of the Macedonian, Albanian and Romany population, by genotyping using long range polymerase chain reac...

Introduction: Cheiloscopy is defined as the study of sulci labiorum, known "lip prints". Aim study: The aim this was to determine morphological characteristics lip grooves in three dominant nationalities Republic North Macedonia (Macedonians, Albanians, Roma) and compare obtained results with other populations from different geographical regions. Material methods: In research, we included 150 e...

bronchial asthma is a multifactorial disease whereby both environmental and genetic factors contribute to its aetiology and/or clinical severity. the aim of this study was to examine the association of 22 cytokine gene polymorphism in the macedonian population with bronchial asthma (ba). the sample of the population comprised of 301 normal unrelated individuals and 74 patients with ba. cytokine...

Mitochondrial DNA polymorphisms were analyzed in of 1,610 randomly chosen adult men from 11 different regions from southeastern Europe (Croatians, Bosnians and Herzegovinians, Serbians, Macedonians and Macedonian Romani). MtDNA HVS-I region together with RFLP sites diagnostic for main Euroasian and African mtDNA haplogroups were typed to determine haplogroup frequency distribution. The most fre...

HLA alleles have been determined in individuals from the Republic of Macedonia by DNA typing and sequencing. HLA-A, -B, -DR, -DQ allele frequencies and extended haplotypes have been for the first time determined and the results compared to those of other Mediterraneans, particularly with their neighbouring Greeks. Genetic distances, neighbor-joining dendrograms and correspondence analysis have ...

Analysis of Y chromosome haplogroups, defined by single nucleotide polymorphisms (SNPs), is now a standard approach for study of the origin of human populations and measurement of the variability among them. It is also a new forensic tool, because it may allow determination of the origin of any male sample of interest. We have used a strategy for rapid, simple and inexpensive Y chromosome SNP t...

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1 1260506&dopt=Abstract Tissue Antigens February 2001, vol. 57, no. 2, pp. 118-127 HLA genes in Macedonians and the sub-Saharan origin of the Greeks A. Arnaiz-Villena; K. Dimitroski; A. Pacho; J. Moscoso; E. Go ́mez-Casado; C. Silvera-Redondo; P. Varela; M. Blagoevska; V. Zdravkovska; J. Martý ́nez-Laso Department of I...