The bone defect repair functions of calcium phosphate cement (CPC) are related to its osteoconductivity and its gradual replacement by new bone. Adding mannitol to CPC may enhance its bone repair potential by increasing CPCs macroporosity and dissolution rate. The objective of the study was to assess microporosity and macroporosity and dissolution rates for CPC mixed with mannitol. Three groups...

We report a facile one-pot synthesis of hierarchically porous scaffolds, with independent control over nanoparticle mesoporosity and scaffold macroporosity. Our technique combines the chemistry of mesoporous silica nanoparticles with the control afforded by dynamic templating of surfactant mesophases. These materials are readily functionalizable and allow controllable spatial variation in macro...

Fatigue and monotonic test specimens having porosity ranging from microto macroscopic levels were cast from 8630 steel. Monotonic and fatigue properties were obtained to determine the effect of porosity on the mechanical performance of the cast steel. Axial fatigue tests were conducted under fully reversed conditions in both strain and load control on specimens containing microporosity, and in ...

In this work, novel injectable calcium phosphate foams (CPFs) were combined with an antibiotic (doxycycline) to design an innovative dosage form for bone regeneration. The material structure, its drug release profile and antibiotic activity were investigated, while its clinical applicability was assessed through cohesion and injectability tests. Doxycycline had a clear effect on both the micro ...

Microspheres with controlled nano- and macroporosity are fabricated by template-assisted spray drying. Increasing the porosity of the particle up to 20% improves the rate performance of the particles as shown experimentally and by electrochemical simulations of particle lithiation.

For tissue engineered bone constructs, calcium phosphate cement (CPC) has a high potential as scaffold material because of its biocompatibility and osteoconductivity. However, in vivo resorption and tissue ingrowth is slow. To address these issues, microspheres can be incorporated into the cement, which will create macroporosity after in situ degradation. The goal of this study was to investiga...

We demonstrate here the ordering of block copolymer micelles by ice templating, below 0 °C. We used this for the preparation of silica monoliths that present an ice-templated macroporosity, combined with a 2D hexagonal mesostructure templated by the addition of P123. We propose a mechanism triggered by the progressive freezing-induced concentration.

Microorganisms are an essential fraction of soil organic matter, which presence and activity depend directly on physical conditions. This study aimed to address the effect temperature moisture under contrasting macroporosity conditions biological properties. Soil physical-chemical characterization implicated collection composite samples undisturbed surface (0 10 cm). Also, were extracted in 40 ...