traneous" hormones, (e) metabolic studies, (f) sensitivity of presumed target organ, (g) effects of removal of certain of the endocrines, (h) effect of hypophysectomy on target organs (related to subject "g"), and (i) graft studies. No student of experimental embryology should be denied the opportunity of reading Jost's essay. Finally, the essay by Greep on the interrelations of pituitary funct...

MAL promoter hypermethylation was examined in 260 human esophageal specimens using real-time quantitative methylation-specific PCR (qMSP). MAL hypermethylation showed highly discriminative ROC curve profiles which clearly distinguished esophageal adenocarcinomas (EAC) from both esophageal squamous cell carcinomas (ESCC) and normal esophagus (NE). Both MAL methylation frequency and normalized me...

landsat data for 1992, 2000, and 2013 land use changes for ekbatan dam watershed was simulated through ca-markov” model. two classification methods were initially used, viz. the maximum likelihood (mal) and support vector machine (svm). although both methods showed high overall accuracy and kappa coefficient, visually mal failed in separating land uses, particularly built up and dry lands.there...

The objective of the present study was to investigate the role of nanocarrier of magnetic isotope of 25-Mg2+ (PMC16) in liver toxicity, ATP content and oxidative stress due to malathion (MAL) exposure. PMC16 nanoparticles were administered in different doses (0.05, 0.1 and 0.2 LD50) intravenously (iv) 40 minutes after a single MAL (0.25 LD50= 207 mg/kg) intraperitoneal (ip) injection as a compl...

Rho GTPases regulate the transcription factor SRF via their ability to induce actin polymerization. SRF activity responds to G actin, but the mechanism of this has remained unclear. We show that Rho-actin signaling regulates the subcellular localization of the myocardin-related SRF coactivator MAL, rearranged in t(1;22)(p13;q13) AML. The MAL-SRF interaction displays the predicted properties of ...

The polarized organization of epithelial cells is required for vectorial solute transport and may be altered in renal cystic diseases. Vesicle integral protein of 17 kDa (VIP17/MAL) is involved in apical vesicle transport. VIP17/MAL overexpression in vivo results in renal cystogenesis of unknown etiology. Renal cystogenesis can occur as a consequence of defects of the primary cilium. To explore...

cases where bayt al-mal is responsible for payment of compensation are sometimes accompanied by intensification of compensation. the question is that whether bayt al-mal should pay the intensified compensation in such cases. this question has not been answered in juristic and, legal texts. in addition to causing difference in opinions, it has caused courts to doubt generalization of the intensi...

We recently identified MAL (T-lymphocyte maturation associated protein) as the most down-regulated gene in cervical oncogenesis. Here, we examined the mechanism underlying MAL silencing, its functional role in cervical carcinogenesis, and the relevance of detecting MAL alterations for risk assessment of hrHPV-positive women. MAL mRNA expression and promoter methylation were analysed in primary ...

The discovery of lymphoid B-Iymphotropic herpesvirus-producing cell lines from M. arctoides peripheral lymphocytes (MAL-l) producing their own lymphotropic virus HVMA was reported earlier [1]. Subsequently, two more M. arctoides virus-producing lymphoid cell lines (MAL-2, MAL-3) were discovered in our laboratory. The cells of some baboon lymphoid cultures, parallel with B-Iymphotropic herpesvir...