SUMMARY A new type of modulation called continuous-phase parallel-combinatory high-compaction multicarrier modulation (CPPC/ HC-MCM) is proposed. CPPC/HC-MCM employs the technique of continuous-phase modulation (CPM) and avoids the formation of amplitude gaps between two successive signals to enhance the spectral efficiency of conventional PC/HC-MCM. Results of simulations show that CPPC/ HC-MC...

The heterohexameric minichromosome maintenance protein complex (Mcm2-7) functions as the eukaryotic helicase during DNA replication. Mcm2-7 loads onto chromatin during early G1 phase but is not converted into an active helicase until much later during S phase. Hence, inactive Mcm complexes are presumed to remain stably bound from early G1 through the completion of S phase. Here, we investigated...

In 2001, IBM delivered to the marketplace a high-performance UNIX-class eServer based on a four-chip multichip module (MCM) code named Regatta. This MCM supports four POWER4 chips, each with 170 million transistors, which utilize the IBM advanced copper back-end interconnect technology. Each chip is attached to the MCM through 7018 flip-chip solder connections. The MCM, fabricated using the IBM...

Eukaryotes have six minichromosome maintenance (MCM) proteins that are essential for DNA replication. The contribution of ATPase activity of MCM complexes to their function in replication is poorly understood. We have established a cell-free system competent for replication in which all MCM proteins are supplied by purified recombinant Xenopus MCM complexes. Recombinant MCM2-7 complex was able ...

Many efficient algorithms and architectures have been introduced for the design of low complexity bit-parallel Multiple Constant Multiplications (MCM) operation which dominates the complexity of many digital signal processing systems. On the other hand, little attention has been given to the digit-serial MCM design that offers alternative low complexity MCM operations. In this paper, we address...

Cell division is a complex process that requires precise duplication of genetic material. Duplication is concerted by replisomes. The Minichromosome Maintenance (MCM) replicative helicase is a crucial component of replisomes. Eukaryotic and archaeal MCM proteins are highly conserved. In fact, archaeal MCMs are powerful tools for elucidating essential features of MCM function. However, while euk...

Hoveyda-Grubbs type catalysts with cationic tags on NHC ligands were linker-free immobilized on the surface of lamellar zeolitic supports (MCM-22, MCM-56, MCM-36) and on mesoporous molecular sieves SBA-15. The activity of prepared hybrid catalysts was tested in olefin metathesis reactions: the activity in ring-closing metathesis of citronellene and N,N-diallyltrifluoroacetamide decreased in the...

A series of mesoporous catalysts (MCM-41) promoted by copper oxide nanoparticles were prepared by the co-precipitation method and tested for the decomposition of carbon tetrafluoride (CF4). The addition of copper oxide nanoparticles to MCM-41 led to an improvement in the catalytic activity for CF4 decomposition. The catalyst was the most active around 5 wt% copper oxide added to MCM-41. Methods...

This work examines whether microglia-conditioned medium (MCM) is beneficial in stressed spinal cord cells or tissues. MCM was separated into two fractions by 50 kDa molecular cut-off centrifugation. MCM not only promoted survival of neuronal and oligodendroglial cells but effectively reduced LPS stimulation in spinal cord cultures. We further utilized the NYU weight-drop device to induce contus...