Mitochondria are dynamic organelles that have inner and outer membranes. In plants, the inner membrane has been well studied but relatively little is known about the outer membrane. Here we report that Arabidopsis cells have mitochondrial outer membrane-derived structures, some of which protrude from the main body of mitochondria (mitochondrial outer-membrane protrusions; MOPs), while others fo...

The mechanisms that ensure the removal of damaged mitochondrial proteins and lipids are critical for the health of the cell, and errors in these pathways are implicated in numerous degenerative diseases. We recently uncovered a new pathway for the selective removal of proteins mediated by mitochondrial derived vesicular carriers (MDVs) that transit to the lysosome. However, it was not determine...

There is possibility of microbial contamination of any single-dose vials (SDVs), multiple-dose vials (MDVs) and admixtures (ADXs) during the preparation and injection to the patients that could be resulted in bloodstream infection. The goal of this study was to investigate the microbial contamination of MDVs and SDVs after multiple use and ADXs prepared by nursing staff in the treatment room ve...

Multi-Designated Verifier Signature (MDVS) is a privacy-oriented signature scheme in which the signature produced can only be verified by a specific set of users. A generic MDVS scheme was proposed recently, which can be constructed from some ring signature schemes and a secure multi-party computation (SMC) protocol. In this paper, we try to remove the requirement of the costly SMC. We propose ...

The messa di voce (MDV) is a vocal exercise used by singers, consisting of a crescendo and decrescendo on a single sustained note. In this study we analysed recorded MDVs sung by tertiary singing students to examine the extent to which MDVs have a linear crescendo and linear decrescendo. The MDVs studied were recorded over a 3-year period, as a cohort of classical singing students progressed th...

Designated verifier signatures (DVS) allow a signer to create a signature whose validity can only be verified by a specific entity chosen by the signer. In addition, the chosen entity, known as the designated verifier, cannot convince any body that the signature is created by the signer. Multi-designated verifiers signatures (MDVS) are a natural extension of DVS in which the signer can choose m...

Mitochondrial respiration relies on electron transport, an essential yet dangerous process in that it leads to the generation of reactive oxygen species (ROS). ROS can be neutralized within the mitochondria through enzymatic activity, yet the mechanism for steady-state removal of oxidized mitochondrial protein complexes and lipids is not well understood. We have previously characterized vesicul...

Multi-Designated Verifier Signatures (MDVS) are privacy-oriented signatures that can only be verified by a set of users specified by the signer. We propose two new generic constructions of MDVS from variants of existing cryptographic schemes, which are ring signature from anonymous subset and multi-chameleon hash. We first devise a single add-on protocol which enables many existing identity-bas...

there is possibility of microbial contamination of any single-dose vials (sdvs), multiple-dose vials (mdvs) and admixtures (adxs) during the preparation and injection to the patients that could be resulted in bloodstream infection. the goal of this study was to investigate the microbial contamination of mdvs and sdvs after multiple use and adxs prepared by nursing staff in the treatment room ve...

There is possibility of microbial contamination of any single-dose vials (SDVs), multiple-dose vials (MDVs) and admixtures (ADXs) during the preparation and injection to the patients that could be resulted in bloodstream infection. The goal of this study was to investigate the microbial contamination of MDVs and SDVs after multiple use and ADXs prepared by nursing staff in the treatment room ve...