New formulations and technologies have been developed through oral drug delivery systems' researches. Such researches display significance of oral route amongst patients. We've reviewed all the features associated with medicated chewing gum as a modern drug delivery by introducing the history, advantages and disadvantages, methods of manufacturing, composition differences, evaluation tests and ...

statement of problem: the role of the microbial plaque in caries etiology and periodontal diseases has been proved and the mechanical methods for plaque control have special limitations, consequently, chemical methods have been suggested. one of the most effective materials is chlorhexidine gluconate that is commonly used as mouth rinses. however, the medicated formulations of chewing gums, due...

In present era, many research and technological advancements are made in the field of oral drug delivery as it is highly accepted amongst patients.. Chewing gum is one of the very popular oral confectionery products. Medicated chewing gums are prepared by using a water insoluble gum base, elastomers, emulsifiers, fillers, waxes, antioxidants, softeners, sweeteners, food colourings, flavoring ag...

Medicated chewing gums are defined by the European Pharmacopoeia 1 and the guidelines for pharmaceutical dosage forms as „„solid single dose preparations with a base consisting mainly of gum that are intended to be chewed but not swallowed, providing a slow steady release of the medicine contained‟‟2. It can be either used for local treatment of mouth disease or systemic delivery by direct intr...

Chewing gums are the type of mobile drug delivery systems. It is useful by means administering drugs either locally or systemically through, oral cavity. The treated chewing gum has through times gained adding acceptance as a medicine system. As compare to that chewable tablets epoxies aren't supposed be swallowed and it can removed from point operation without resort invasive biting gum. MCG s...

The aim of the present work is development and evaluation of Chlorpheniramine maleate medicated chewing gums and to study the influence of different plasticizers on physicochemical parameters and in vitro drug release profile. Chlorpheniramine maleate is used to relieve symptoms of allergy, hay fever and common cold. Prepared formulations are evaluated for thickness, hardness, weight variation,...

People of all cultures chew gum, and a variety of gums and gum-like substances have been enjoyed for thousands of years. The introduction and subsequent success of Nicotine chewing gum in the 1980’s paved the way for a more general acceptance of chewing gum as a drug delivery system. Improved technology and extended knowledge, together with the inclusion of medical chewing gum in the European P...

BACKGROUND Extrinsic staining of teeth may result from the deposition of a variety of pigments into or onto the tooth surface, which originate mainly from diet or from tobacco use. More recently, clinical studies have demonstrated the efficacy of some chewing gums in removing extrinsic tooth staining. The aim of this study was to assess the effectiveness of two nicotine medicated chewing gums (...