the coexistence of medullary thyroid carcinoma (mtc), papillary thyroid carcinoma (ptc) and parathyroid adenoma is an uncommon clinical entity. here, we report a case of mtc, ptc, and parathyroid adenoma diagnosed incidentally on a routine physical examination of the neck for the work-up of diabetes. the patient had neither symptoms of hypercalcemia nor those related to mtc and ptc.

introduction: medullary thyroid carcinoma (mtc) is a rare thyroid cancer secreting calcitonin (ct) which is the most sensitive and specific tumor marker for mtc. this type of thyroid cancer is able to metastasize to different body areas including regional lymph nodes, lungs, liver and bone. the aim of this study was to assess the sensitivity and specificity of [99mtc-dmsa (v)] whole body scan (...

Medullary thyroid carcinoma (MTC) is an infrequent calcitonin-producing neuroendocrine tumor that initiates from the parafollicular C cells of the thyroid gland. Several genetic and epigenetic alterations are collaterally responsible for medullary thyroid carcinogenesis. In this review article, we shed light on all the genetic and epigenetic hallmarks of MTC. From the genetic perspective, RET, ...

radioiodine (1-131) is the treatment of choice in differentiated thyroid carcinoma. external radiotlierapy however, has it's own roie in these tumors. treatment of anaplastic thyroid carcinoma 1ms not acliieved any notahle success yet, though combined - modality regimens of radiotherapy and chemotherapy have sometimes shown significant results. in this paper the role of radiotlierapy and chemot...

  Radioiodine (1-131) is the treatment of choice in differentiated thyroid carcinoma. External radiotlierapy however, has it's own roie in these tumors. Treatment of anaplastic thyroid carcinoma 1ms not acliieved any notahle success yet, though combined - modality regimens of radiotherapy and chemotherapy have sometimes shown significant results. In this paper the rol...

Parathyroid carcinoma is the rarest endocrine cancer with aggressive behaviour. It may be presented as a feature of severe hypercalcemia, musculoskeletal involvement and neck mass. There should high clinical suspicion if there marked very parathyroid hormone levels, palpable mass, recurrent laryngeal nerve palsy due to invasion bone renal symptoms. Thyroid pathology has been seen in 15-70% pati...

  We report an unusual case of a young male with cerebellar hemangioblastoma treated previously for medullary carcinoma of thyroid, whose PET/CT scans revealed a constellation of findings that suggested the rare Von Hippel Lindau syndrome. The diagnosis was clinched by confirming the findings on whole body contrast enhanced computed tomography (CECT) and contrast enha...

UNLABELLED INTRODUCTION Papillary thyroid microcarcinoma has been demonstrated to present in association with medullary thyroid carcinoma, however, medullary thyroid carcinoma and papillary thyroid carcinoma represent rare entities. In recent years this rarity has been increasingly observed. The pathogenesis is still controversial. Genetic analysis of RET proto-oncogenes in cases of simultan...