conclusions phoma glomerata pg41 strain sharing natural substrate with toxigenic a. flavus secretes metabolites possessing a significant aflatoxin-degrading activity. the activity is associated mainly with a protein-enriched high-molecular-weight fraction of extracellular metabolites and appears to be of enzymatic origin. results the afb1-degrading activity of protein-enriched fractions, isolat...

Metabolites of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a potent pulmonary carcinogen, have been quantified in the urine of 11 smokers. They were not detected in nonsmokers' urine. The metabolites, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronide, were detected in quantities of 0.23-1.0 and 0.57-6.5 micrograms/24 h, respectively. The res...

Traditional methods for assessing dietary exposure can be unreliable, with under reporting one of the main problems. In an attempt to overcome such problems there is increasing interest in identifying biomarkers of dietary intake to provide a more accurate measurement. Metabolomics is an analytical technique that aims to identify and quantify small metabolites. Recently, there has been an incre...

microbial steroid biotransformation have found wide-reaching application for the production of more precious and functionalized compounds due to their high regio-and stereoselectivity. in this study, the possibility of using filamentous fungi aspergillus brasiliensis cells in the biotransformation of progesterone (i), a c-21 steroid hormone was studied for the first time.the fungal strain was i...

in biotechnology has been concentrated to review alternative routes for the production of natural compounds. plant cell culture systems are viable alternatives for the production of secondary metabolites that are of commercial importance in food and pharmaceutical industries. however, relatively very few cultures synthesize these compounds over extended periods in amounts comparable to those fo...

this study was carried out to evaluate the effects of satureja khuzistanica essential oils (skeo) on performance, serum metabolites and differential counts of white blood cells in broiler chickens. a total of 280 one-day-old straight-run cobb 500 broiler chickens were allocated into seven treatment groups with four replicates of 10 birds each from day 1 to 42 of age. the birds were continuously...

boraginaceae family is known as a medicinal plant classified in dicotyledons.  it is originated from asia (middle east). the aim of this study was to evaluate ingredient between 4 species of boraginaceae family based on physiological & phytochemical traits as well as seed fatty acid contents.  4 species (e. russicum, e. italicum, e. amoenum, and b. officinalis ) were evaluated carefully. all se...