a procedure was developed for rapid in vitro germination of linum album seeds by scarification and exposing to gibberellic acid (ga3) and kinetin (kn).  concentrations of podophyllotoxin (ptox) and related aryltetralin lignans α-peltatin, β-peltatin, 5’-demethoxy-6-methoxypodophyllotoxin and 6-methoxypodophyllotoxin (mptox) in l. album fresh plant organs were determined by hplc. a degree of var...

The cross-resistances of several mutants of Chinese hamster ovary cells which have been obtained after one and two selection steps in the presence of the microtubule inhibitor podophyllotoxin ( P o d R~ and P o d R" mutants, respectively) towards various other inhibitors of microtubule assembly (e .g . , colchicine, Colcemid, vinblastine, griseofulvin, maytansine, steganacin, nocodazole, and ta...

The cross-resistances of several mutants of Chinese hamster ovary cells which have been obtained after one and two selection steps in the presence of the microtubule inhibitor podophyllotoxin ( P o d R~ and P o d R" mutants, respectively) towards various other inhibitors of microtubule assembly (e .g . , colchicine, Colcemid, vinblastine, griseofulvin, maytansine, steganacin, nocodazole, and ta...

      A procedure was developed for rapid in vitro germination of Linum album seeds by scarification and exposing to gibberellic acid (GA3) and kinetin (Kn).  Concentrations of podophyllotoxin (PTOX) and related aryltetralin lignans α-peltatin, β-peltatin, 5’-demethoxy-6-methoxypodophyllotoxin and 6-methoxypodophyllotoxin (MPTOX) in L. album fresh plant org...

Deguelin, a plant-derived rotenoid, mediates potent chemopreventive responses through transcriptional regulation of phorbol ester-induced ornithine decarboxylase (ODC) activity. To explore the mechanism of this effect, the activity of this compound was evaluated with a number of modelsystems.Usingculturedmouseepidermal308cells,thesteady-state levels of both 12-0-tetradecanoylphorbol-13-acetate ...

Human blood neutrophil granulocytes (neutrophils) treated with Podophyllum peltatum L.-derived compounds exhibited an enhanced oxidative response to subsequent challenge with bacterial formyl peptides. This priming effect was concerned with superoxide anion (O2-) release (respiratory burst). The phenomenon was observed with a potentized preparation containing, among other things, podophyllum ex...