The regulation of cell motility by ligand density on substrates with variable microtopography is not well understood. In this report, we studied the adhesion and motility behavior of HepG2 cells on microtextured poly(glycolic-co-lactic)acid (PGLA) copolymer substrates, whose surface bioactivity was differentially modified through the adsorption of 0-5.5 ng/cm(2) collagen. Microtextured PGLA sub...

To evaluate the effect of surface treatment and surface microtexture on cellular behavior, smooth and microtextured silicone substrata were produced. The microtextured substrata possessed parallel surface grooves with a width and spacing of 2.0 (SilD02), 5.0 (SilD05), and 10 microns (SilD10). The groove depth was approximately 0.5 microns. Subsequently, these substrata were either left untreate...

This study investigated the bone-to-implant contact (BIC) and osteoconductive capacity (OC) of 6 different implant surfaces after early loading in humans. Two implants with different surfaces were placed side-by-side in the grafted (n= 5) and nongrafted (n = 1) sinuses of 3 volunteers. Single-tooth restorations were delivered 60 days later. After 6 months of full occlusal loading, implants were...

Microtextured superhydrophobic surfaces have become ubiquitous in a myriad of engineering applications. These surfaces have shown potential in friction reduction applications and could be poised to make a big impact in thermal management applications. For instance higher heat transfer rate with less pumping power might be achievable through the aid of superhydrophobic surfaces. However, past an...

conclusions consequently, this study shows promising results for il of single implants, and it can be considerable that treatment with microtextured surface implants is a predictable and appropriate method of treatment. background the immediate loading (il) protocol has gained increased popularity among surgeons in the last decade. objectives this study aimed to evaluate the clinical performanc...

Polystyrene-poly(acrylic acid) (PS-PAA) block copolymers polymerized by atom transfer radical polymerization were covalently grafted to both smooth and microtextured surfaces. These amphiphilic copolymers were utilized to create smart surfaces, which can be responsive to external stimuli, e.g., pH values or organic solvent. Atom force microscopy, field emission scanning electron microscopy, and...

Fibroblasts have been shown to respond to substratum surface roughness. The change in cell size, shape and orientation of rat dermal fibroblasts (RDF) was therefore studied using smooth and microtextured silicone rubber substrata. The microtextured substrata possessed parallel surface microgrooves that ranged in width from 1.0 to 10.0 microns, and were separated by ridges of 1.0 to 10.0 microns...

The success of dental implants is primarily dependent upon the degree of osseointegration or bone-to-implant contact (BIC), possibly facilitated by a roughened implant surface. This study was performed to histologically evaluate the nature of osseointegration and bone healing of submerged microtextured implants in eight dogs. Three months following tooth extraction in the posterior mandibulae, ...

The purpose of this paper is to demonstrate the easy manufacturing and quick characterization several microtextured functional surfaces on two transparent thermoplastics general interest for industrial sectors. Microtextured polymeric with special optical, tribological easy-cleaning properties were manufactured via isothermal injection-molding using laser-microtextured steel mold inserts. For t...

It has been suggested that during wound healing microtextured surfaces can alter events at the interface between implant surface surface and surrounding tissues. To investigate this phenomenon, smooth and microtextured silicone rubber implants were implanted subcutaneously in rabbits for 3, 7, 42, and 84 days. The textured implants possessed parallel surface microgrooves and ridges with a width...