نتایج جستجو برای: mineralization

تعداد نتایج: 13215  

Journal: :Frontiers in bioscience : a journal and virtual library 2007
Leonie F A Huitema Arie B Vaandrager

Mineralization is an essential requirement for normal skeletal development, but under certain pathological conditions organs like articular cartilage and cardiovascular tissue are prone to unwanted mineralization. Recent findings suggest that the mechanisms regulating skeletal mineralization may be similar to those regulating pathological mineralization. In general, three forms of cell-mediated...

Journal: :Genes & development 2005
Monzur Murshed Dympna Harmey José Luis Millán Marc D McKee Gerard Karsenty

Extracellular matrix (ECM) mineralization is a physiological process in bone and a pathological one in soft tissues. The mechanisms determining the spatial restriction of ECM mineralization to bone physiologically are poorly understood. Here we show that a normal extracellular phosphate concentration is required for bone mineralization, while lowering this concentration prevents mineralization ...

2015
Svetlana V. Komarova Lee Safranek Jay Gopalakrishnan Miao-jung Yvonne Ou Marc D. McKee Monzur Murshed Frank Rauch Erica Zuhr

Defective bone mineralization has serious clinical manifestations, including deformities and fractures, but the regulation of this extracellular process is not fully understood. We have developed a mathematical model consisting of ordinary differential equations that describe collagen maturation, production and degradation of inhibitors, and mineral nucleation and growth. We examined the roles ...

2017
Li-Na Niu Sang Eun Jee Kai Jiao Lige Tonggu Mo Li Liguo Wang Yao-Dong Yang Ji-Hong Bian Lorenzo Breschi Seung Soon Jang Ji-Hua Chen David H Pashley Franklin R Tay

Mineralization of fibrillar collagen with biomimetic process-directing agents has enabled scientists to gain insight into the potential mechanisms involved in intrafibrillar mineralization. Here, by using polycation- and polyanion-directed intrafibrillar mineralization, we challenge the popular paradigm that electrostatic attraction is solely responsible for polyelectrolyte-directed intrafibril...

Journal: :Applied and environmental microbiology 2012
Jacob Bælum Emmanuel Prestat Maude M David Bjarne W Strobel Carsten S Jacobsen

Mineralization potentials, rates, and kinetics of the three phenoxy acid (PA) herbicides, 2,4-dichlorophenoxyacetic acid (2,4-D), 4-chloro-2-methylphenoxyacetic acid (MCPA), and 2-(4-chloro-2-methylphenoxy)propanoic acid (MCPP), were investigated and compared in 15 soils collected from five continents. The mineralization patterns were fitted by zero/linear or exponential growth forms of the thr...

2015
Aya Hashimoto Yoshinori Yamaguchi Liang-da Chiu Chiaki Morimoto Katsumasa Fujita Masahide Takedachi Satoshi Kawata Shinya Murakami Eiichi Tamiya

Osteoblastic mineralization occurs during the early stages of bone formation. During this mineralization, hydroxyapatite (HA), a major component of bone, is synthesized, generating hard tissue. Many of the mechanisms driving biomineralization remain unclear because the traditional biochemical assays used to investigate them are destructive techniques incompatible with viable cells. To determine...

Journal: :زمین شناسی اقتصادی 0
آزاده ملکزاده شفارودی محمد رضا حیدریان شهری محمد حسن کریم پور

maherabad prospect area, which is studied in detail, is the first porphyry cu-au mineralization in the east of iran. based on relation of mineralization with subvolcanic intrusive bodies mostly monzonitic with porphyry texture, extent and types of alteration including potassic, sericitic- potassic, quartz- sericite- carbonate- pyrite, quartz- carbonate- pyrite, silicification- propylitic, propy...

Journal: :Chemosphere 2005
Juliana A Ramsay Kevin Robertson Gary vanLoon Nick Acay Bruce A Ramsay

Amendment of a soil slurry with low concentrations of a cyclodextrin, hydroxypropyl-beta-cyclodextrin (HPCD), (0.05-0.5 g l(-1)) increased the phenanthrene mineralization rate of a microbial consortium by 25% under Fe(III)-reducing conditions. Although a higher concentration (5.0 g l(-1)) resulted in a faster initial rate of mineralization, mineralization ceased after 25 days with maximum miner...

Journal: :Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association 2009
Christina A Bradbury Jodi L Westropp Rachel E Pollard

Canine prostatic disease is commonly evaluated with abdominal ultrasound and radiographs. Mineralization of the prostate is often reported, but the clinical relevance of this finding is currently not known. The-purpose of this study was to characterize the relationship between ultrasonographic and radiographic prostate mineralization and the final diagnosis. Medical records of 55 dogs with evid...

Journal: :Bone 2012
Jordan McCormack Susan M Stover Jeffery C Gibeling David P Fyhrie

We recently developed a method to measure cortical bone fracture initiation toughness using a double-notched beam in four-point bending. This method was used to test the hypothesis that mineralization around the two notch roots is correlated with fracture toughness and crack extension (physical damage). Total energy absorbed to failure negatively correlated with average mineralization of the be...

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