This review considers modern data on the morphology and functions of mitochondria in neurons glial cells various brain structures laboratory rodents. We discuss main aspects intracellular regional heterogeneity neuronal mitochondria. The functional differences between different cerebral regions are highlighted. analyze structural features gliocytes as well their role maintaining glioneuronal in...

Cellular differentiation induces various morphological changes, including elongation, in mitochondria. Preimplantation embryos have round-shaped mitochondria, characteristic of undifferentiated cells. However, there is controversy regarding the precise mitochondrial morphology blastocyst embryos, which are generated from two cell lineages : inner mass (ICM) and differentiated trophectoderm (TE)...

If your body were a train, what would give it the power to move? The food you eat, which is burned by train’s engine. Do know how many engines has? Thousands of millions! They are called mitochondria. Mitochondria tiny structures contained within cells that burn food, providing energy. each mitochondrion due its own gearwheel: circular mitochondrial DNA. There gears in mitochondrion. Together, ...

glaucoma is the second leading cause of irreversible blindness and a neurodegenerative disease with a complex pathogenesis. increasing evidence suggests that oxidative stress and mitochondrial dysfunction have crucial roles in most neurodegenerative diseases such as glaucoma. the conventional clinical treatment for glaucoma is lowering the intraocular pressure (iop). some patients have normal i...

Common techniques for the treatment of Hepatocellular carcinoma (HCC) have not been successful, and thus the design and discovery of new compounds with better anti-cancer function are needed. Snake venom is among the most important compounds used by researchers to the treatment of various cancers. This study was designed to evaluate the toxicity effect of Persian Gulf snake venom (Enhydrina sch...

Background: Mitochondria are a source of reactive oxygen species (ROS), and several natural compounds used as antioxidant agents. This study aimed to investigate compare the effects fresh grape juice red wine on oxidative stress biomarkers in rat liver mitochondria. Materials Methods: In this regard, mitochondria were isolated from 27 male Wistar rats (220-250 g). The cultured different doses f...

The number of people with neurodegenerative disease continues to increase every year. A new perspective is needed overcome this disease. In review, researchers collected information about dysfunctional energy in diseases driven by mitochondria. Mitochondrial dysregulation can cause damage the neuron system. amount and interaction α-synuclein SAMM50 GABARAPL1 mitochondria one factors causing As ...

Mitochondria are one of the most important organelles for eukaryotes, including humans, to produce energy. In energy-producing process, mitochondria constantly generate reactive oxygen species as a by-product electrons leaking out from electron transport chain react with oxygen. The active oxygen, in turn, plays pivotal roles mediating several signalings, those that implicated development some ...

objective: the urinary system of euryhaline fish, as well as the gills, is involved in ion regulation through the production of dilute urine in freshwater and isotonic urine in seawater. the low osmolality of the urine originates from an active reabsorption of ions by ionocytes or mitochondria rich-cells (mrcs) present in certain parts of the urinary system. mitochondria rich-cells possess a hi...

chamaemelum nobile (asteraceae) commonly known as 'roman chamomile' is a medicinal plant used for numerous diseases in traditional medicine, although its anticancer activity is unknown. the present study was carried out to investigate the anticancer as well as apoptotic activity of ethyl acetate fraction of c. nobile on different cancerous cell lines. the cells were treated with varyi...