نتایج جستجو برای: mrna expression
تعداد نتایج: 925408 فیلتر نتایج به سال:
background: granuloca cells have a key role during estroeidogenesis. objectives: the purpose of this study was to determine the effect of number of culture medium granulosa cells on estradiol concentrations and mrna codding estrogenic and progestagenic enzyme. methods: briefly, follicles between 2 and 5 mm diameter were dissected from the ovaries of adult cows and were collected by rinsing the ...
Background and purpose: Visual deprivation during critical period of brain development impairs structure and function of NMDA receptors in visual cortex. Parts of visual signals go to the hippocampus through the visual cortex. Therefore, this study aimed at investigating the effects of visual deprivation during critical period of brain development on NMDA receptor subunits expression in rats’ h...
objective(s): cd44 is a member of the cell adhesion molecules family. naturally, cd44s, along with cd44v3 influence the cell motility, migration, and adhesion, while in tumor cells they lead to tumor invasion, progression, and metastasis. the purpose of this research is to evaluate the cd44s and cd44v3 expression in esophageal squamous cell carcinoma (escc) and to reveal their correlations wit...
the study was conducted to demonstrate expression profile of cold shock protein genes; cold inducible rna binding protein (cirp) and rna binding motif protein 3 (rbm3) in goats (capra hircus) during different seasons to check the gene expression in different thermal conditions. blood samples were collected from healthy goats of tropical and temperate region during peak winter, moderate season a...
Abstract Objective: The previous studies indicated that the TLRs especially Toll-like receptor 4) TLR4 (are involved in the process of diabetes. The aim of the present research was to investigate the time course expression pattern of TLR4-a main component of innate immune system- in mRNA levels in the heart tissue of diabetic male wistar rats. Materials and Methods: In this research, adu...
background: the conventional chemotherapeutic regimens which applied for treatment of acute myeloid leukemia (aml) mostly target tumor bulk but not leukemic stem cells (lscs). aberrant expression or activation of mediators such as osteopontin (opn) or pi3k/pten/akt/mtor pathway plays a key role in making prone to develop leukemia. preventing or treating cancer by curcumin (cur) has been suggest...
Introduction: The aim of the present study was to investigate the expression of estrogen-related receptor alpha (ERRα) - an important factor in cellular energy homeostasis regulation - in skeletal muscle of male Wistar rats after four weeks of endurance training and to determine its role with fat metabolism indexes. Methods: In this experimental study, 30 male Wistar rats (eight weeks-ol...
background: little in known regarding the clinical relevance of sirt1 in multiple sclerosis (ms). here, we aimed to evaluate mrna expression, protein level and enzyme activity of sirt1 in peripheral blood mononuclear cells (pbmcs) isolated from relapsing –remitting ms patients (rrms) and healthy controls. materials and methods: twenty patients with rr-ms and twenty two age- and sex-matched he...
Introduction: Multidrug resistance (MDR) is the main obstacle against treatment of acute lymphoblastic leukemia (ALL). ATP-binding cassette transporters function is mentioned as one of the most effective factors on MDR development. Though, there are many evidences on interference of ABCG2/BCRP, one of the outstanding members of this superfamly, in MDR occurrence, the expression effect of this g...
background: black seed (bs) is used in traditional medicine as a therapy for a variety of diseases including allergic asthma. materials and methods: in the present study, anti-inflammatory and immunomodulatory effects of bs on cytokine gene expression, lung airway eosinophilia and goblet cell hyperplasia were examined in a mouse mice model of allergic asthma. groups of 6-week-old female balb/c ...
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