This paper gives the first correlation bounds under product distributions (including the uniform distribution) against the class mNC of poly(n)-size O(log n)-depth monotone circuits. Our main theorem, proved using the pathset complexity framework recently introduced in [56], shows that the average-case k-CYCLE problem (on Erdős-Rényi random graphs with an appropriate edge density) is 12 + 1 pol...

Introduction Digital transformation has been promoted by the World Health Organization (WHO), Food and Drug Administration (FDA) European Commission (EC) to help improve health outcomes. To ensure sustainability, digital interventions (DHI) require funding payers. Evidence-informed decision policy making requires an assessment of impact on relevant outcomes vs current healthcare practice. Vario...

BACKGROUND Mucins are heavily O-glycosylated proteins where the glycosylation has been shown to play an important role in cancer. Normal epithelial ovarian cells do not express secreted mucins, but their abnormal expression has previously been described in epithelial ovarian cancer and may relate to tumor formation and progression. The cyst fluids were shown to be a rich source for acidic glyco...

DISCLAIMER: This report is based on information available at the time of research cannot be expected to cover any developments arising from subsequent improvements health technologies. This report is based on a limited literature search and is not a definitive statement on the safety, effectiveness or cost-effectiveness of the health technology covered. The Commonwealth does not guarantee the a...

Health technology assessment (HTA) has become an integral part of health policy generation and is actively supported by many government agencies throughout the world. When performed within the framework of evidence-based medicine (EBM), such evaluations have the potential to guide clinicians and patients regarding the appropriate use of new technologies and as to their safety. EBM is oriented t...

The robust regression techniques in the RANSAC family are popular today in computer vision, but their performance depends on a user supplied threshold. We eliminate this drawback of RANSAC by reformulating another robust method, the M-estimator, as a projection pursuit optimization problem. The projection based pbM-estimator automatically derives the threshold from univariate kernel density est...

T HE benefits of lightweight space robotic manipulators are gained at the expense of higher elasticity in the joints. This leads to a more complex dynamic behavior. The additional flexible dynamics introduce two more state variables for each joint, which implies that the description of the complete dynamics model (including joint elasticity) requires four states for each joint: position and vel...

Experiments that assign intact groups to treatment conditions are increasingly common in social research. In educational research, the groups assigned are often schools. The design of group randomized experiments requires knowledge of the intraclass correlation structure to compute statistical power and sample sizes required to achieve adequate power. This paper provides a compilation of intrac...