نتایج جستجو برای: multiple chromosomal changes
تعداد نتایج: 1613428 فیلتر نتایج به سال:
an experimental study was accomplished to compare estimation methods of ionizing radiations genotoxicity in mammalian cell cultures by means of two cytogenetic parameters with focus on aberrant cells characterized by multiple chromosomal damages.in vitro study was carried out on the genotoxicity of low-medium doses of 190 kv x-rays absorbed in chinese hamster ovary cell cultures. micronuclei an...
BACKGROUND In multiple sclerosis (MS), treatment discontinuation leads to a higher risk of relapse, poorer quality of life and greater economic impact. OBJECTIVE The objective of this work is to evaluate treatment discontinuation in MS, the reasons for this and the reasons for treatment resumption. METHODS A French national Web-based survey was carried out between May and August 2011. A tot...
Background: Nonlethal genetic damage is the basis for carcinogenesis. As various gene aberrations accumulate, malignant tumors are formed, regardless of whether the genetic damage is subtle or large enough to be distinguished in a karyotype. The study of chromosomal changes in tumor cells is important in the identification of oncogenes and tumor suppressor genes by molecular cloning of genes in...
Background & Aims: The study of karyotype in several cases is the first step in the diagnosis of genetic disorders. The purpose of this study was to investigate the karyotype of a number of individuals with a range of possible genetic disorders. Materials & Methods: This researchis a descriptive cross-sectional study. Sampling was done after obtaining necessary permissions and written consent ...
Several studies have verified the existence of multiple chromosomal abnormalities in colon cancer. However, the relationships between DNA copy number and gene expression have not been adequately explored nor globally monitored during the progression of the disease. In this work, three types of array-generated data (expression, single nucleotide polymorphism, and comparative genomic hybridizatio...
objective: chromosomal aberrations are common causes of multiple anomaly syndromes. recurrent chromosomal aberrations have been identified by conventional cytogenetic methods used widely as one of the most important clinical diagnostic techniques. materials and methods: in this retrospective study, the incidences of chromosomal aberrations were evaluated in a six year period from 2005 to 2011 i...
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