dear editor multiple sclerosis (ms) is the most common inflammatory demyelinating disease of the central nervous system. ms is characterized by dissemination in time and place. dissemination can be clinically (clinically definite multiple sclerosis) or radiologically by magnetic resonance imaging (mri). correct diagnosis of ms needs dissemination both in time and in place and also exclusion of ...

multiple sclerosis (ms) is an autoimmune disease of the central nervous system associated to myelin loss and neurodegeneration. clinically patients suffer from diverse symptoms and face the risk to become wheelchair-bound. at the moment ms is incurable, thus there is an unmet need for therapeutic options.

conclusions the results of this study showed a possible association between cmv infection and ms. further experimental and epidemiological studies using case-control approaches are needed to confirm this association. results anti-cmv was positive in 65 (79.3%) and 69 (77.5%) of the ms patients and healthy subjects, respectively (p= 0.853). similarly, 23 (28%) and 2 (2.2%) patients were positive...

background: there has been a global rising trend in recent years in the incidence of multiple sclerosis (ms). despite being an ms low-risk region, this disease has also been recently on the rise in the middle east. as part of the middle east, iran has not been spared either; however, the cause of this dramatic increase remains to be discovered. the present study reviews possible reasons for thi...

multiple sclerosis is an autoimmune disease caused by damage to the myelin of the nerve cells in the spinal cord and brain, ms was classified into 4 types including: relasping/remitting (rr) primary/progressive (pp), secondary/progressive (sp), progressive/relapsing (pr). pr ms is one of the severe forms of ms that lead to inflammation associated physical, mental and vision dysfunction. because...

multiple sclerosis (ms) is an autoimmune inflammatory process that affects the central nervous system (cns). celiac disease (cd) is a systemic autoimmune disorder of gluten intolerance. based on the presumed association of ms with multiple autoimmune processes, the coincidence of ms with gluten sensitivity has been investigated with controversial results. here, we report a known case of ms with...

introduction: the purpose of this study was to visualize the scientific structure of multiple sclerosis (ms) during 1999-2008 and to use scientometric indicators for analysis of ms-related scientific publications indexed in web of science database. methods: this survey tried to visualize data as a scientometric method. a total number of 17737 ms-related articles published during 1999-2008 were ...

high cortisol level in endogenous cushing’s syndrome suppresses the immune system and after treatment there may be an over activity of immune reaction leading to autoimmune diseases mostly thyroid and rheumatologic disorders. this is the second reported case of multiple sclerosis developing after treatment of cushing’s syndrome. a 42-year old man is reported who presented with bone fracture and...

to understand the mechanism of multiple sclerosis (ms), an autoimmune demyelinating disease, the researchers developed an experimental animal model for ms, which is called eae (experimental allergic encephalomyelitis). there are several methods for inducing this animal model. in this research the active eae, which is developed by injecting bovine myelin antigens into genetically susceptible ani...

neuromyelitis optica is an inflammatory demyelinating disease (idd) of the cns, which mainly affects optic nerve and spinal cord. autoantibodies against aquaporin-4 also known as nmo-igg have been implicated in the pathogenesis of nmo. we evaluated the sensitivity and specificity of nmo-igg assay for diagnosing nmo patients and differentiating them from ms patients and those with undifferentiat...