نتایج جستجو برای: mupirocin

تعداد نتایج: 891  

2015
Sung Hee Youn Seung Soon Lee Sukyeon Kim Jeong-a Lee Bum Joon Kim Jounghee Kim Hye-kyung Han Jae-Seok Kim

BACKGROUND/AIMS Intranasal mupirocin and chlorhexidine bathing are candidate strategies to prevent healthcare-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA). In Korea, intranasal mupirocin is not available, and mupirocin ointment, an over-the-counter drug, has been used indiscriminately. Furthermore, because it is covered by health insurance, mupirocin is eas...

2012
Se Young Park Shin Moo Kim Seok Don Park

BACKGROUND Mupirocin has been used for the treatment of skin infections and eradication of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA). The increased use of this antibiotic has been accompanied by outbreaks of MRSA that are resistant to mupirocin. OBJECTIVE This study aims to determine the prevalence, genotype and antimicrobial susceptibility of mupirocin-resistant MR...

Journal: :Antimicrobial agents and chemotherapy 2015
Nina K Antonov Maria C Garzon Kimberly D Morel Susan Whittier Paul J Planet Christine T Lauren

Topical mupirocin is used widely to treat skin and soft tissue infections and to eradicate nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA). Few studies to date have characterized the rates of S. aureus mupirocin resistance in pediatric populations. We retrospectively studied 358 unique S. aureus isolates obtained from 249 children seen in a predominantly outpatient setting ...

Journal: :The American journal of medicine 1993
C A Kauffman M S Terpenning X He L T Zarins M A Ramsey K A Jorgensen W S Sottile S F Bradley

PURPOSE To assess the impact of the use of mupirocin ointment on colonization, transmission, and infection with methicillin-resistant Staphylococcus aureus (MRSA) in a long-term-care facility. PATIENTS AND METHODS All 321 residents of a Veterans Affairs long-term-care facility from June 1990 through June 1991 were studied for MRSA colonization and infection. MRSA-colonized patients received m...

Journal: :Journal of clinical microbiology 2010
Jacob S Hogue Patricia Buttke LoRanee E Braun Mary P Fairchok

We investigated the proportion of methicillin-resistant Staphylococcus aureus (MRSA) isolates from pediatric patients demonstrating mupirocin resistance related to mupirocin use at our institution. No mupirocin resistance was found in 98% of isolates, whereas mupirocin prescriptions increased by 110%. Resistance rates remained low despite the increasing use of mupirocin.

Journal: :Annals of dermatology 2015
Sang Hyun Park Jin Kyung Kim Kun Park

BACKGROUND The in vitro activities of retapamulin and fusidic acid against clinical isolates of mupirocin-resistant and methicillin-resistant Staphylococcus aureus (MRSA) from Korea are not well understood. OBJECTIVE This study aimed to determine the activities of retapamulin and fusidic acid against clinical isolates of mupirocin-resistant MRSA. METHODS Clinical isolates of mupirocin-resis...

Journal: :The Journal of hospital infection 2010
A R Caffrey B J Quilliam K L LaPlante

Implementation of meticillin-resistant Staphylococcus aureus (MRSA) decolonisation programmes has been increasing and the emergence of mupirocin resistance has been reported. However, the patient-level risk factors associated with mupirocin resistance are not clear. In this study, independent predictors of mupirocin resistance in MRSA among Providence Veterans Affairs Medical Center patients wi...

Journal: :The Journal of antimicrobial chemotherapy 2015
David J Hetem H Charles Vogely Tim T Severs Annet Troelstra Johannes G Kusters Marc J M Bonten

OBJECTIVES The association between mupirocin use and plasmid-based high-level resistance development mediated through mupA in CoNS has not been quantified. We determined acquisition of mupirocin resistance in Staphylococcus aureus and CoNS in surgery patients treated peri-operatively with mupirocin. PATIENTS AND METHODS Patients admitted for surgery were treated with nasal mupirocin ointment ...

2015
TANUSHREE BISWAS MUNMUN DAS SARKAR

Mupirocin is a topical antimicrobial agent utilized in treatment of methicillin resistant Staphylococcus aureus. Mupirocin resistance in Staphylococcus aureus is increasingly being reported in many parts of the world in the context of its widespread use. The objectives of this study were to determine the susceptibility of methicillin resistant Staphylococcus aureus clinical isolates to mupiroci...

Journal: :The Journal of antimicrobial chemotherapy 2005
Julian G Hurdle Alex J O'Neill Lona Mody Ian Chopra Suzanne F Bradley

OBJECTIVES We examined the molecular basis of the emergence of mupirocin resistance in a methicillin-resistant Staphylococcus aureus (MRSA) strain colonizing a nursing home resident undergoing mupirocin prophylaxis. PATIENT AND METHODS A persistent carrier of mupirocin-susceptible MRSA participated in a trial of mupirocin for nasal decolonization among nursing home residents. During prophylax...

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