TGF-β1 is known to inhibit muscle regeneration after muscle injury. However, it is unknown if high systemic levels of TGF-β can affect the muscle regeneration process. In the present study, we demonstrated the effect of a CCl₄ intra-peritoneal injection and losartan (an angiotensin II type 1 receptor antagonist) on skeletal muscle (gastrocnemius muscle) injury and regeneration. Male C57BL/6 mic...

We present a case of a torn pronator teres muscle of the right forearm that occurred following prolonged batting during recreational cricket. Previous reports of cricket injuries to batsmen describe phalanx fractures due to direct ball impact. However, we could find no prior reports of pronator teres or other upper-extremity muscle injury. Our patient demonstrated a high-grade tear to the prona...

BACKGROUND Volumetric muscle loss (VML) following extremity orthopaedic trauma or surgery results in chronic functional deficits and disability. A current translational approach to address the devastating functional limitations due to VML injury is the use of an autologous minced muscle graft (~1 mm3 pieces of muscle tissue) replacement into the injured defect area, although limitations related...

Temporary or permanent vocal cord paralysis caused by recurrent laryngeal nerve injury is one of the relatively common and serious complications thyroid surgery. At same time, there are many reasons for injury. Therefore, should be paid attention to before, during after A 51-year-old woman was diagnosed with left papillary carcinoma. Unfortunately, patient had a history hoarseness following pat...

Modified muscle use or injury can produce a stereotypic inflammatory response in which neutrophils rapidly invade, followed by macrophages. This inflammatory response coincides with muscle repair, regeneration, and growth, which involve activation and proliferation of satellite cells, followed by their terminal differentiation. Recent investigations have begun to explore the relationship betwee...

Objective(s): When the nerve is injured near its entrance to the muscle belly, we cannot perform conventional methods. One useful method in such a situation is neurotization surgery. In this study, Bone marrow mesenchymal stem cells (BMSCs) implanted into the paralyzed muscle after neurotization surgery. These cells can stimulate axon growth and motor endplate formation, also prevent muscle atr...

PURPOSE This study examined the subacute myotoxic effects of injection of the local anesthetic bupivacaine on the orbicularis oculi muscle in the rabbit eyelid. In contrast to other muscles, the orbicularis oculi was resistant to injury by the usual anesthetic doses of bupivacaine when local infiltration is used. An attempt was made to assess the sensitivity of orbicularis oculi muscle to bupiv...

Muscle lesions are among the most common injuries encountered in performance sports. Despite their high incidence, diagnosis, classification, and treatment constantly being debated. Most of time, severity injury indicates recovery strategy (conservative, physical therapy, surgical, etc). Currently, due to advances medical, pharmacological, muscle can be greatly improved. Incomplete or incorrect...