Mycobaterium bovis is among a pathogenic species which belongs to the Mycobacterium tuberculosis complex (MTBC), a group of genetically closely related mycobacteria [1]. Mycobaterium bovis (M. bovis) is an intracellular, non-motile, facultative, weakly Gram-positive acid-fast bacillus [2]. The MTBC sub-group also comprises M. tuberculosis, M. africanum, M. canettii, M. pinnipedii, M. microti an...

Mycobaterium bovis is among a pathogenic species which belongs to the Mycobacterium tuberculosis complex (MTBC), a group of genetically closely related mycobacteria [1]. Mycobaterium bovis (M. bovis) is an intracellular, non-motile, facultative, weakly Gram-positive acid-fast bacillus [2]. The MTBC sub-group also comprises M. tuberculosis, M. africanum, M. canettii, M. pinnipedii, M. microti an...

Methods This prospective study was done at NMC, Nellore from July 2008-December 2009. Samples received at microbiology lab for acid fast staining were included in this study. Smears were stained by Ziehl-Neelsen’s technique. Samples were cultured on Lowenstein-Jensen media after processing by modified Petroff’s method and incubated according to CLSI guidelines. Identification of Mycobaterium tu...

current researches have showed that n3, n5-diaryl-2, 6-dimethyl -1, 4-dihydropyrine-3, 5- dicarboxamide analogues demonstrate notable anti-tubercular activity. in this study, hantzsch condensation was used to design and synthesize new analogues of dihydropyridine (dhp). different diary carboxamides were inserted at positions 3 and 5 of the dhp ring. 4(5)-chloro-2-ethyl-5(4)-imidazolyl moiety wa...

Around 50 mycobacteria species cause human disease. Immunosuppressive states predispose to non-tuberculous mycobaterium infection, such as Mycobacterium chelonae: AFB, non-tuberculous, fast growth of low virulence and uncommon as a human pathogen. It may compromise the skin and soft tissues, lungs, lymph nodes and there is also a disseminated presentation. The diagnosis involves AFB identificat...

The aim of the article is to describe the principal findings among patients with M.tuberculosis and M. bovis CNS infection. Mycobacterium tuberculosis is one of the most common infectious agents that cause death and neurological sequelae around the world. Most of the complications of CNS TB can be attributed to a delay in the diagnosis. Unfortunately, there are no specific diagnostic tools to s...

Tuberculosis is a serious global public health problem and its high prevalence is strongly associated with the increase of drug resistance. This steady increase in the frequency of M. tuberculosis strains resistant to one or more agents commonly used to treat tuberculosis has drawn worldwide attention to understanding the molecular basis of resistance in M. tuberculosis. TB resistance is a grea...